BMJ:姑息治疗对终末期非肿瘤患者的意义

2020-07-13 MedSci原创 MedSci原创

姑息治疗对改善晚期慢性器官衰竭患者生活质量有益,但会增加痴呆晚期患者医疗负担

近日研究院人员在加拿大安大略省,考察了2010年至2015年间非肿瘤终末期患者接受姑息治疗的效果。
 
研究期间,113540名死于癌症和非癌症疾病的成年人,在生命的最后六个月接受了姑息治疗。研究的主要终点为接受姑息治疗后患者急诊就诊率、入院率、重症监护率,以及居家或住院死亡率,根据患者特征(如年龄、性别和并存病)进行调整。
 
在死于与慢性器官衰竭(如心力衰竭、肝硬化和中风)相关的非肿瘤疾病患者中,与未接受姑息治疗的患者相比,姑息治疗可降低患者急诊(调整后的比率为0.88)、住院(0.88)和重症监护住院率(0.59)风险。此外,与住院死亡相比,姑且治疗与居家或疗养院死亡率增加相关(n=6936(49.5%)vs n=9526(39.6%);调整优势比1.67)。与慢性器官衰竭疾病相反,痴呆症死亡患者接受姑息治疗后与急诊就诊率(1.06)和入院率(1.33)增加有关,并且居家或养老院死亡率降低(n=6667(72.1%)vs n=13384(83.5%);调整率比率0.68)。
 
研究发现,姑息治疗对改善晚期慢性器官衰竭患者生活质量有益,但会增加痴呆晚期患者医疗负担。
 
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    2020-10-06 gaoxiaoe
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    2020-07-13 lovetcm

    #姑息治疗#姑息治疗在中国相对落后,大家关注的比较少,到底归属于临床学科还是营养科,没有定论

    0

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