Diabetes Care:中国近20万人4C研究称:应常规检测餐后2小时血糖,因其预测糖尿病和心血管病效果更好

2019-09-26 文韬 中国循环杂志

中国入选近20万人的4C研究发现,为更好地评估糖尿病、心血管疾病、癌症和死亡风险,除了检测空腹血糖和糖化血红蛋白(HbA1c)外,也应将常规检测餐后2小时血糖。

中国入选近20万人的4C研究发现,为更好地评估糖尿病、心血管疾病、癌症和死亡风险,除了检测空腹血糖和糖化血红蛋白(HbA1c)外,也应将常规检测餐后2小时血糖。

研究表明,餐后2小时血糖比空腹血糖和HbA1c的预测糖尿病和上述疾病的效果更好。

作者认为,餐后高血糖在病理生理与空腹高血糖不同,比如存在如胰岛素抵抗,或晚时相胰岛素分泌受损,因此能提高额外的预测价值。

研究发现,空腹血糖、餐后2小时血糖和HbA1c升高都预测糖尿病及其并发症。

但即使纳入空腹血糖和HbA1c指标后,餐后2小时血糖仍然与糖尿病、心血管疾病、癌症、全因死亡率风险增加显著相关。

而且,餐后2小时血糖升高显著提高了糖尿病、心血管疾病和全因死亡率的预测能力。

在糖尿病前期患者中,仅餐后2小时血糖诊断的糖尿病前期患者的心血管疾病和全因死亡风险增加。

4C研究是一项多中心、基于人群的前瞻性队列研究,目的是研究血糖与临床结局的关系,包括糖尿病、心血管疾病、癌症和全因死亡率等。

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    2019-09-26 misszhang

    谢谢MedSci提供最新的资讯

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1761211, encodeId=87bd1e6121176, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Fri Oct 18 23:05:00 CST 2019, time=2019-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1639229, encodeId=fb371639229f4, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Sep 10 08:05:00 CST 2020, time=2020-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1902324, encodeId=1b59190232424, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Thu Oct 17 20:05:00 CST 2019, time=2019-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1644789, encodeId=b8171644e891e, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Wed Jul 15 18:05:00 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042735, encodeId=504c1042e3567, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Thu Sep 26 12:05:00 CST 2019, time=2019-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046915, encodeId=a7b410469150d, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Thu Sep 26 12:05:00 CST 2019, time=2019-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=373215, encodeId=a5b33e321511, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/03/0e492dda8bcc1f98474b74c2863aca87.jpg, createdBy=068d2446376, createdName=Dr Z, createdTime=Thu Sep 26 09:46:28 CST 2019, time=2019-09-26, status=1, ipAttribution=)]
    2019-09-26 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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    2019-09-26 Dr Z

    学习了

    0