ABO血型那点事儿

2016-12-05 华西医院实验医学科 韩冰 检验医学网微信

不少人认为血型就是A型、B型、O型、AB型嘛。这样的认识比较片面。血型是指血液成分(包括红细胞、白细胞、血小板)表面的抗原类型,通常所说的血型是指红细胞膜上特异性抗原类型,根据抗原类型的不同分为不同的血型系统,目前已知的有35个红细胞血型系统,而与临床关系最密切和大家最为熟悉的是ABO血型系统。今天我们就来聊聊大家关心的ABO血型那点事儿。ABO血型ABO血型是根据红细胞膜上是否存在抗原A与抗原B

不少人认为血型就是A型、B型、O型、AB型嘛。这样的认识比较片面。血型是指血液成分(包括红细胞、白细胞、血小板)表面的抗原类型,通常所说的血型是指红细胞膜上特异性抗原类型,根据抗原类型的不同分为不同的血型系统,目前已知的有35个红细胞血型系统,而与临床关系最密切和大家最为熟悉的是ABO血型系统。今天我们就来聊聊大家关心的ABO血型那点事儿。




ABO血型


ABO血型是根据红细胞膜上是否存在抗原A与抗原B而将血液分成4种血型。红细胞上仅有抗原A为A型,只有抗原B为B型,若同时存在A和B抗原则为AB型,这两种抗原俱无的为O型。我国人群中A型、B型及O型血各占约30%,AB型仅占10%左右。


ABO血型的遗传


父母双亲的血型可以遗传给子女。简单来说,O型血不带显性基因,A型和B型血各携带一个显性基因和一个隐性基因,AB型血带有两个显性基因。子女会分别获得一条来自父母的遗传基因,如来自一方的遗传基因是显性基因,那么子女就会将这个血型继承下来,如果来自父母双方的都是隐性基因,则后代的血型就会是O型。所以,我们可以根据父母的血型粗略判断子女可能的血型。如今,我们可以轻易在网络上查到“血型遗传规律表”,其中例举了各种父母血型的组合生出的子女可能和不可能的血型。这里需要注意的一点是,在一些罕见的血型,如顺式AB型的人来说,O型和AB型的父母也可以生出O型或AB型的子女;因此运用血型来判断亲缘关系过于“简单粗暴”了,对于这一类问题,还是应该借助于正规的亲子鉴定。


ABO血型与性格有关吗?


日本学者古川竹二于1927 年提出了“人因血型不同, 而具有各自不同的气质;同一血型, 具有共同的气质”的论断。古川认为A 型的人内向保守、多疑焦虑、富感情、缺乏果断性、容易灰心丧气等。B 型的人外向积极、善交际、感觉灵敏、轻诺言、好管闲事等。O 型的人胆大、好胜、喜欢指挥别人、自信、意志坚强、积极进取等。AB 型的人兼有A型和B 型的特征。

当然,这种说法在学术界并没有得到认可,大部分的研究并不支持这种血型论,即使是那些报告血型与性格有显著性相关的研究,其结果也是模棱两可,甚至是相互矛盾的。

奇怪的是,血型性格说在民间却奇迹般地被广为接受。这或许与星座性格论有异曲同工之处,老百姓多了一点茶余饭后的有趣谈资而已。


ABO血型与疾病


如果说,血型与性格的关系并不靠谱的话,血型与疾病的关系可是有科学依据的哦。国内外学者对血型与疾病的关系做了不少研究。例如,急性脑血管病中,A型人群占有很高的比例。另外,B型人易患心血管疾病,有学者在对瑞士AMI(急性心肌梗死)人群研究发现, ABO血型系统中的B等位基因是AMI的独立危险因素,而O1 等位基因是AMI的保护性因素, 这可能与不同基因型人群中vW F水平高低有关,而高水平vWF正是AMI发病的高危因素。国内学者研究发现O型人幽门螺杆菌阳性率高,而幽门螺杆菌感染与慢性胃炎、胃十二指肠溃疡有着极为密切的关系

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    2016-12-11 Jackie Li

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    2016-12-08 Jackie Li

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    2016-12-07 TZF0804
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    2016-12-07 闆锋旦
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    2016-12-06 MyQueen

    A型性格

    0

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    2016-12-06 susice

    学习了,谢谢!

    0

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    2016-12-06 wodexinxi

    A型血Aa的和AA基因型的人红细胞表面抗原表达有没有差异?

    0

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    2016-12-05 尹玉伟

    这个我到现在还是不太明白……

    0

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    2016-12-05 1e19caf7m97(暂无匿称)

    AB型飘过

    0

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