Materials:三维印刷钛合金的原位控制表面微观结构促进其整合

2019-03-14 不详 网络

众所周知,三维(3D)印刷是一种新兴技术,用于制备额定制植入物和植入物的表面特征,改善其骨整合能力。在该研究中,在合适的合理印刷参数下印刷Ti合金微球,以便通过原位控制方式在增材制造期间调整印刷植入物的表面微观特征。激光路径和阴影空间是造成条状结构(S)外观的原因,而球状结构(B)和球状-复合材料表面(BS)是通过轮廓扫描确定的。纳米尺寸的结构可以通过水热处理叠加。通过培养小鼠颅盖衍生的前成骨细胞

众所周知,三维(3D)印刷是一种新兴技术,用于制备额定制植入物和植入物的表面特征,改善其骨整合能力。

在该研究中,在合适的合理印刷参数下印刷Ti合金微球,以便通过原位控制方式在增材制造期间调整印刷植入物的表面微观特征。激光路径和阴影空间是造成条状结构(S)外观的原因,而球状结构(B)和球状-复合材料表面(BS)是通过轮廓扫描确定的。纳米尺寸的结构可以通过水热处理叠加。通过培养小鼠颅盖衍生的前成骨细胞(MC3T3-E1)评估细胞相容性。

结果表明,通过改变3D打印参数可以实现三个典型的微结构表面S,B和BS。此外,S,B和BS表面的成骨分化潜能可以显著增强,并且可以进一步改善纳米尺寸结构的添加。具有纳米尺寸结构的BS表面显示出最佳的成骨分化潜能。

本研究表明,在具有较高骨整合能力的植入物的3D打印过程中,可以采用原位,受控的方式来定制和优化微尺寸的表面结构。

原始出处:

Shan L, Kadhum AAH, et al., In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration. Materials (Basel). 2019 Mar 10;12(5). pii: E815. doi: 10.3390/ma12050815.

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    2019-09-05 30397613
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    2019-03-16 楚秀娟
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    2019-03-16 swallow