Dig Dis Sci:股静脉壁厚度可能是区分白塞氏病与肠内感染和克罗恩氏病的独特诊断工具

2020-10-06 MedSci原创 MedSci原创

白塞病(BD)是一种全身性炎症性疾病,其特征是口腔和生殖器溃疡,其他表现以及包括主要血管,肌肉骨骼,神经系统和胃肠道(GI)系统在内的全身性受累。

        白塞病(BD)是一种全身性炎症性疾病,其特征是口腔和生殖器溃疡,其他表现以及包括主要血管,肌肉骨骼,神经系统和胃肠道(GI)系统在内的全身性受累。BD中的胃肠道系统(GI)受累通常表现为腹痛,然后是腹泻,出血,呕吐,排便习惯改变,体重减轻,瘘管和穿孔,所有这些表现在炎性肠病中也会经常发生。BD和CD也具有一些遗传背景和免疫病原相似性,例如IL-17 / 23途径。由于相似的肠外表现,在具有非特异性胃肠道表现的年轻人中,这两种疾病不易区分。最近有研究发现:股总静脉(CFV)厚度的增加是BD的一个显着特征,单很少出现在其他炎症或血管疾病中,对于≥0.5 mm的CFV厚度,诊断BD特异性高于80%。因此,本项研究评估CFV厚度诊断在BD和CD鉴别诊断中的诊断性能。

 

        研究人员收集了BD(n  = 69),CD(n  = 38)和健康对照(HC)(n  = 38)的患者各若干名。用多普勒超声仪测量双边CFV厚度,然后使用ROC曲线判断CFV在诊断疾病准确度中的效能。

 

        与HC和CD相比,BD的左右CFV厚度均显着更高(右:0.76 mm VS 0.33 mm,左:0.78 mm VS 0.35 mm, 两者p <0.001)。CD中的CFV厚度与HC相似( 两者均p > 0.05)。在有和没有胃肠道受累的BD患者之间,CFV厚度也相似(p = 0.367)。CFV厚度的诊断截断值≥0.5 mm,对于CD和HC都可很好地区分BD。阳性和阴性预测值> 90%。

 

        研究人员最后说道:与BD相比,CD的CFV厚度要低得多,CFV壁厚测量可能是区分BD和CD的独特诊断工具,可在日常实践中帮助区分两种疾病。

 

 

 

原始出处:

Fatma Alibaz-Oner. Et al. Femoral Vein Wall Thickness Measurement May Be a Distinctive Diagnostic Tool to Differentiate Behçet’s Disease with Intestinal Involvement and Crohn’s Disease. Digestive Diseases and Sciences.2020.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1723637, encodeId=1a0a1e23637be, content=<a href='/topic/show?id=7b08915917b' target=_blank style='color:#2F92EE;'>#诊断工具#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91591, encryptionId=7b08915917b, topicName=诊断工具)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c37033510464, createdName=surilei, createdTime=Sun Oct 11 05:15:46 CST 2020, time=2020-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013494, encodeId=366f2013494aa, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Thu Sep 09 15:15:46 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1698151, encodeId=5d6e1698151b5, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Mon Feb 08 08:15:46 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2003492, encodeId=348020034927f, content=<a href='/topic/show?id=5b592889555' target=_blank style='color:#2F92EE;'>#克罗恩氏病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28895, encryptionId=5b592889555, topicName=克罗恩氏病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=139a316, createdName=wumeihua88, createdTime=Thu Jan 14 23:15:46 CST 2021, time=2021-01-14, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1723637, encodeId=1a0a1e23637be, content=<a href='/topic/show?id=7b08915917b' target=_blank style='color:#2F92EE;'>#诊断工具#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91591, encryptionId=7b08915917b, topicName=诊断工具)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c37033510464, createdName=surilei, createdTime=Sun Oct 11 05:15:46 CST 2020, time=2020-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013494, encodeId=366f2013494aa, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Thu Sep 09 15:15:46 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1698151, encodeId=5d6e1698151b5, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Mon Feb 08 08:15:46 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2003492, encodeId=348020034927f, content=<a href='/topic/show?id=5b592889555' target=_blank style='color:#2F92EE;'>#克罗恩氏病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28895, encryptionId=5b592889555, topicName=克罗恩氏病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=139a316, createdName=wumeihua88, createdTime=Thu Jan 14 23:15:46 CST 2021, time=2021-01-14, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1723637, encodeId=1a0a1e23637be, content=<a href='/topic/show?id=7b08915917b' target=_blank style='color:#2F92EE;'>#诊断工具#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91591, encryptionId=7b08915917b, topicName=诊断工具)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c37033510464, createdName=surilei, createdTime=Sun Oct 11 05:15:46 CST 2020, time=2020-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013494, encodeId=366f2013494aa, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Thu Sep 09 15:15:46 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1698151, encodeId=5d6e1698151b5, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Mon Feb 08 08:15:46 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2003492, encodeId=348020034927f, content=<a href='/topic/show?id=5b592889555' target=_blank style='color:#2F92EE;'>#克罗恩氏病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28895, encryptionId=5b592889555, topicName=克罗恩氏病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=139a316, createdName=wumeihua88, createdTime=Thu Jan 14 23:15:46 CST 2021, time=2021-01-14, status=1, ipAttribution=)]
    2021-02-08 fusion
  4. [GetPortalCommentsPageByObjectIdResponse(id=1723637, encodeId=1a0a1e23637be, content=<a href='/topic/show?id=7b08915917b' target=_blank style='color:#2F92EE;'>#诊断工具#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91591, encryptionId=7b08915917b, topicName=诊断工具)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c37033510464, createdName=surilei, createdTime=Sun Oct 11 05:15:46 CST 2020, time=2020-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013494, encodeId=366f2013494aa, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Thu Sep 09 15:15:46 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1698151, encodeId=5d6e1698151b5, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Mon Feb 08 08:15:46 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2003492, encodeId=348020034927f, content=<a href='/topic/show?id=5b592889555' target=_blank style='color:#2F92EE;'>#克罗恩氏病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28895, encryptionId=5b592889555, topicName=克罗恩氏病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=139a316, createdName=wumeihua88, createdTime=Thu Jan 14 23:15:46 CST 2021, time=2021-01-14, status=1, ipAttribution=)]

相关资讯

IBD:粪钙卫蛋白浓度是CD患者内镜下粘膜愈合的生物标志物

克罗恩病(CD)是一种炎症性肠病(IBD),其特征是胃肠道的慢性炎症反复发作。患者经常出现的腹泻和疲劳会导致与健康相关的生活质量明显降低。

CELL:克罗恩病患者肠道中的“爬行脂肪”元凶竟是肠道菌群

脂肪组织的显著可塑性被认为是为了储存多余的能量或为饥荒时期做储备而存在的。已有的研究显示,脂肪并不是一个被动的组织,而是一个由多种细胞类型组成的复杂环境,它们能够对许多生理过程作出反应并产生影响。

Dig Dis Sci:回结肠切除术后吻合口溃疡可以预测克罗恩病术后复发

大多数克罗恩病(CD)的患者在其一生中需要接受一次手术治疗,手术可有效缓解疾病的发展,回盲切除术是最常见的手术方法之一。

GUT: 单一硫唑嘌呤可有效治疗溃疡性结肠炎,但对克罗恩病无效

硫嘌呤类似物硫唑嘌呤(AZA)和6-巯基嘌呤(6MP)在炎症性肠病(IBD)的治疗中一直占有一席之地。

IBD:上皮细胞生物标记物可预测克罗恩病对生物制剂的反应

生物制剂是针对特定炎症途径的抗体药物,目前已广泛用于治疗中度至重度炎症性肠病(IBD),包括克罗恩病(CD)和溃疡性结肠炎(UC)。

AJG:新末端回肠的内镜术后复发而非吻合口的术后内镜复发是导致克罗恩病的长期结果的主要诱因

术后第一年内进行早期结肠镜检查是评估回结肠切除术克罗恩病(CD)患者术后复发的金标准。该研究的目的是评估术后早期结肠镜检查中吻合口和回肠病变的存在与严重程度与长期预后之间的关系。