AAN等学会共同发布糖尿病神经病变疼痛处理指南(附指南下载)

2011-04-28 MedSci原创 MedSci原创

2011年4月11日,美国神经病学会(AAN)、美国神经肌肉和电子诊断医学会及物理医学与康复学会共同发布了《糖尿病神经病变疼痛(PDN)处理指南》。   研究者对1960~2008年间的相关文献进行系统综述,并依据AAN有关治疗性文献的证据分类标准对纳入的研究进行分类,以明确在PDN患者中使用的药物(抗惊厥药、抗抑郁药和阿片类等)和非药物(电刺激、磁场治疗、低强度激光治疗和瑜伽等)治疗在减轻疼痛

2011年4月11日,美国神经病学会(AAN)、美国神经肌肉和电子诊断医学会及物理医学与康复学会共同发布了《糖尿病神经病变疼痛(PDN)处理指南》。   研究者对1960~2008年间的相关文献进行系统综述,并依据AAN有关治疗性文献的证据分类标准对纳入的研究进行分类,以明确在PDN患者中使用的药物(抗惊厥药、抗抑郁药和阿片类等)和非药物(电刺激、磁场治疗、低强度激光治疗和瑜伽等)治疗在减轻疼痛及改善躯体功能和生活质量(QOL)方面的有效性。   指南小组认为,目前已存在治疗PDN的有效方法,但多数因副作用而限制了其应用;而关于各种治疗对躯体功能和QOL的影响方面,较少有研究提供充分信息。         疼痛医学的发展,逐步揭示了神经病理疼痛(NP)发生发展的规律,即,用同种机制可以解释多种症状,不同患者的相同症状可能由不同机制引起,多种机制可在一个患者身上共存,患者不同时期的症状可由不同机制引起。NP共同的病理生理学基础改变是,细胞膜兴奋性增高导致异常放电、抑制丢失、外周及中枢敏感化及出现去神经性超敏感现象等。   糖尿病神经病变疼痛(PDN)是典型的NP,其发生过程几乎涵盖了上述

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    2011-05-09 zhouzhiying

    非常好

    0

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    2011-04-30 bluefate123
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    2011-04-30 axin012
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