Stroke:藏族非急性卒中患者白质病变的患病率和危险因素

2019-11-04 xing.T MedSci原创

由此可见,对于居住在高海拔地区的藏人和居住在平原上的个人来说,WML的危险因素似乎相似。需要进行进一步的调查以确定居住在高海拔地区的藏人是否比平原居民具有更高的WML负担。

关于生活在高海拔地区的藏族人白质病变(WML)的患病率和危险因素的研究很少。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员进行了这项研究,以确定没有或患有非急性卒中藏族患者WML的患病率和风险。

研究人员对在西藏自治区人民医院接受治疗的患者病历进行了回顾性分析,共确定了301名没有急性卒中的藏族患者。WML严重程度通过Fazekas量表进行分级。研究人员评估了WML的总体和特定年龄段的患病率,并使用单变量和多变量方法分析了WML与相关因素之间的关联。

在301名患者中,87名(28.9%)患有周围性眩晕,83名(27.3%)患有原发性头痛,52名(17.3%)有卒中病史,36名(12.0%)有焦虑症,29名(9.6%)有癫痫病史,12名(4.0%)患有中枢神经系统感染,3名(1.0%)疾病尚未确。WML存在于245名(81.4%)患者中,其中54名(17.9%)患者年龄小于40岁。单因素分析表明,年龄、脑梗塞病史、高血压、颈总动脉内膜厚度以及颈内动脉斑块是发生WML的危险因素。有序Logistic分析表明年龄、脑缺血性卒中病史、高血压、男性和房颤与WML严重程度有关。

由此可见,对于居住在高海拔地区的藏人和居住在平原上的个人来说,WML的危险因素似乎相似。需要进行进一步的调查以确定居住在高海拔地区的藏人是否比平原居民具有更高的WML负担。

原始出处:

Haiqiang Jin.et al.Prevalence and Risk Factors of White Matter Lesions in Tibetan Patients Without Acute Stroke.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.027115

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    2019-11-05 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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