Gynecol Obstet Invest:UAE治疗CSP后清宫时出血的危险因素

2015-05-16 MedSci MedSci原创

剖宫产术后子宫瘢痕处妊娠(CSP)是指孕卵、绒毛或胚胎着床于子宫既往剖宫产瘢痕处,是一种极罕见的异位妊娠,事实上是一种特殊的子宫肌层妊娠,是一种剖宫产远期并发症。近 几年随着剖宫产率的增高,此病发生率有明显升高趋势。子宫动脉栓塞术(UAE)是通过股动脉行Seldinger穿刺,将直径约3mm的导管在透视监视下送入子宫动脉,经造影证实导管已进入子宫动脉,而后释放栓塞剂栓塞子宫动脉,可以达到预防出血和

剖宫产术后子宫瘢痕处妊娠(CSP)是指孕卵、绒毛或胚胎着床于子宫既往剖宫产瘢痕处,是一种极罕见的异位妊娠,事实上是一种特殊的子宫肌层妊娠,是一种剖宫产远期并发症。近 几年随着剖宫产率的增高,此病发生率有明显升高趋势。


子宫动脉栓塞术(UAE)是通过股动脉行Seldinger穿刺,将直径约3mm的导管在透视监视下送入子宫动脉,经造影证实导管已进入子宫动脉,而后释放栓塞剂栓塞子宫动脉,可以达到预防出血和止血的作用。

对剖宫产术后子宫瘢痕处妊娠(CSP)进行贸然清宫,很容易出现大出血等并发症,而清宫前进行子宫动脉栓塞术(UAE)则为大出血等情况的发生提供了一定的保障,但是并不是说对切口妊娠患者行了子宫动脉栓塞就一定100%的不会出血。近期Du YJ等人专门就这一诊疗情况进行了病理对照试验,探究对剖宫产术后子宫瘢痕处妊娠(CSP)清宫前行子宫动脉栓塞术(UAE)后再清宫时的出血风险。

该研究共纳入了35名CSP患者,经过UAE治疗,在清宫过程中有出血情况,同时纳入140名清宫过程中没有出血的患者作为对照组。研究者收集了患者的孕周、妊娠物与膀胱距离以及阴道出血量等数据。

研究结果显示,经UAE治疗的患者中有6名进行了输血治疗,2名进行了子宫切除术,而对照组没有出现输血治疗或是子宫切除术等情况。研究者通过多变量分析发现,CSP组患者的出血与其孕周和妊娠物与膀胱距离有关。相比于对照组,CSP组患者孕周对出血的影响OR值为1.579 (95% CI 1.291-1.933);妊娠物与膀胱距离对出血的影响OR值为0.208 (95% CI 0.082-0.531)。

研究结果表明,对行了子宫动脉栓塞术(UAE)的剖宫产术后子宫瘢痕处妊娠(CSP)孕妇行清宫术,其孕龄越大,出血风险越大;而妊娠物距离膀胱>0.2 cm则其出血风险小。

原始出处:

Du YJ, Zhang XH, Wang LQ. Risk Factors for Haemorrhage during Suction Curettage after Uterine Artery Embolization for Treating Caesarean Scar Pregnancy: A Case-Control Study. Gynecol Obstet Invest. 2015 .

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    2016-04-29 yhy100200
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