ATVB:血压和心率与隐匿性脑梗塞与脑白质疏松症的恶化风险增加相关!

2017-07-05 xing.T MedSci原创

由此可见,升高的平均收缩压与隐匿性脑梗塞的风险增加相关,而平均舒张压升高与脑白质疏松症恶化的风险增加相关。这些发现强调了高血压在无症状脑血管病发病中的重要性,但它们之间的病理生理关系可能不同。

在既往没有卒中的患者中,通过序列磁共振成像(MRI)发线的隐匿性脑梗塞和脑白质疏松症恶化与缺血性卒中和痴呆的风险增加有关。近日,心血管领域权威杂志Arteriosclerosis, Thrombosis, and Vascular Biology上发表了一篇研究文章,研究人员评估了各种血压和心率的测量指标是否与这些MRI结果相关。心血管健康研究(CHS研究)是一个在老年人中进行的纵向队列研究,研究人员使用相对风险回归评估了每年4次的门诊随访的收缩压、舒张压和心率平均、变异性和趋势与2次大脑核磁共振成像上隐匿性脑梗塞和白质等级恶化(采用10点量表来描述脑白质疏松症)之间的相关性。研究人员纳入了在卒中前和随访后进行了两次大脑核磁共振成像检查以及在随访期间抗高血压药物使用状态没有改变的参与者。在878例符合条件的参与者中,15%的患者发生隐匿性脑梗塞,27%患者白质分级加重。平均收缩压与隐匿性脑梗塞发生风险增加相关(相对危险度为10mmHg,1.28;95%可信区间,1.12-1.47),平均舒张压与白质恶化的风险增加相关(每10mmHg相对危险度为1.45;95%可信区间为1.24-1.6

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    2017-08-17 gongliu
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  5. 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objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Jul 05 15:10:31 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218858, encodeId=1dad21885874, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Jul 05 14:53:47 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218848, encodeId=d11c21884887, content=学习了受益匪浅。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Jul 05 14:46:47 CST 2017, time=2017-07-05, status=1, ipAttribution=)]
    2017-07-07 karmond
  6. 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  7. 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objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Jul 05 15:10:31 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218858, encodeId=1dad21885874, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Jul 05 14:53:47 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218848, encodeId=d11c21884887, content=学习了受益匪浅。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Jul 05 14:46:47 CST 2017, time=2017-07-05, status=1, ipAttribution=)]
    2017-07-06 海棠胜雪

    学习了

    0

  8. 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level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98480, encryptionId=5dbc98480ef, topicName=隐匿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1caf19894563, createdName=41514493@qq.com, createdTime=Fri Jul 07 04:12:00 CST 2017, time=2017-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=219052, encodeId=585421905231, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuCl4zaE0zq0kFsKQmg3vef7gFticiaFX50TWZibZibNHbk3YSJ5uSh1a0DcUiaVIHkoe2Om3eYg7oUTlf/0, createdBy=442c2063958, createdName=海棠胜雪, createdTime=Thu Jul 06 07:31:08 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218864, encodeId=8453218864cc, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Jul 05 15:10:31 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218858, encodeId=1dad21885874, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Jul 05 14:53:47 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218848, encodeId=d11c21884887, content=学习了受益匪浅。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Jul 05 14:46:47 CST 2017, time=2017-07-05, status=1, ipAttribution=)]
    2017-07-05 Y—xianghai

    学习了新知识

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1977958, encodeId=9ff119e79582f, content=<a href='/topic/show?id=20411e958de' target=_blank style='color:#2F92EE;'>#TVB#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17958, encryptionId=20411e958de, topicName=TVB)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1a5a149, createdName=gongliu, createdTime=Thu Aug 17 03:12:00 CST 2017, time=2017-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765643, encodeId=31721e65643ce, content=<a href='/topic/show?id=252ae1803a3' target=_blank style='color:#2F92EE;'>#白质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71803, encryptionId=252ae1803a3, topicName=白质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, 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level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98480, encryptionId=5dbc98480ef, topicName=隐匿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1caf19894563, createdName=41514493@qq.com, createdTime=Fri Jul 07 04:12:00 CST 2017, time=2017-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=219052, encodeId=585421905231, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuCl4zaE0zq0kFsKQmg3vef7gFticiaFX50TWZibZibNHbk3YSJ5uSh1a0DcUiaVIHkoe2Om3eYg7oUTlf/0, createdBy=442c2063958, createdName=海棠胜雪, createdTime=Thu Jul 06 07:31:08 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218864, encodeId=8453218864cc, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Jul 05 15:10:31 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218858, encodeId=1dad21885874, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Jul 05 14:53:47 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218848, encodeId=d11c21884887, content=学习了受益匪浅。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Jul 05 14:46:47 CST 2017, time=2017-07-05, status=1, ipAttribution=)]
    2017-07-05 Y—xianghai

    学习了新知识

    0

  10. 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encodeId=d11c21884887, content=学习了受益匪浅。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Jul 05 14:46:47 CST 2017, time=2017-07-05, status=1, ipAttribution=)]
    2017-07-05 131****1460

    学习了受益匪浅。

    0

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总之,在血液透析患者中,尽管透析单元内SBP与心血管疾病风险存在U形(矛盾)关联,但透析单元外SBP与心血管疾病的风险存在线性关联。透析单位外血压提供了关键信息,并可能是一个重要的治疗靶标。

Eur Heart J:缺血性卒中患者的血压和住院预后之间的相关性分析!

在入院缺血性脑卒中住院患者中,可以观察到血压与短期结局之间存在J形或U形的关系。溶栓治疗后出血并发症随血压降低而较低。

电子血压计误差并不大!

电子血压计在生活中已越来越普及,但对于它检测可能不准的担忧也一直存在。辽宁省人民医院心血管内科主任医师关汝明告诉《生命时报》记者,市场上销售的各式电子血压计,几乎都采用“示波法”测量,即检测气袖内因血管壁搏动而引起的震荡波。传统水银柱血压计采用的则是“科氏音法”,即通过听诊器来听血管内血液流动的声音。虽然测量原理不同,但测试结果从理论上讲是一样的。

Atherosclerosis:上臂动脉血压差异和冠状动脉粥样硬化发病

双臂动脉血压差异(IABPD)增大已经证实和动脉粥样硬化发生有关,但是是否和冠状动脉疾病发生有关目前还未知。本试验旨在研究IABPD和冠状动脉粥样硬化发病的关系。我们对初次行冠状动脉造影的患者同时测量双臂血压,对血压的数据记性回顾性的研究。在冠脉造影的结果基础上,使用Gensini评分对冠状动脉硬化程度进行评估。为了调整基础血压的影响,分别计算双臂收缩压差高于平均血压百分率(cIABPDsys)、

JAHA:动脉硬化程度的种族差异主要是由血压水平决定的

由此可见,cf-PWV的种族差异主要是由于平均动脉压和年龄的差异所致,尽管他们不能完全解释最高cf-PWV值的女性种族和cf-PWV之间的相关性。这表明克服衰老对血管系统影响的治疗方法应该集中在血压控制上,尤其是在黑人人群中。