Circulation:感染SARS-CoV-2的年轻运动员心脏受累情况

2021-04-18 MedSci原创 MedSci原创

SARS-CoV-2感染的年轻运动员短期随访中心脏受累患病率和临床事件风险均较低。

重症急性呼吸综合征冠状病毒2(SARS-CoV-2)住院患者心脏受累较为常见,并与不良结局相关。近日,血管领域权威杂志Circulation上发表了一篇研究文章,这项研究旨在明确年轻运动员感染SARS-CoV-2后心脏受累的患病率及其临床意义。

在这项前瞻性多中心观察性队列研究中,研究人员从42所大学的数据中评估了美国大学生运动员中因SARS-CoV-2感染心脏受累的患病率、临床特征以及结局。数据收集自2020年9月1日至2020年12月31日。该研究的主要结局是根据更新的路易斯湖准则所定义的影像学明确的、极可能的或可能发生的SARS-CoV-2心脏受累的患病率。次要结局包括心脏检测的诊断率,心脏受累的预测因子以及不良心血管事件或住院。

在19378名接受SARS-CoV-2感染检测的运动员中,3018名(平均年龄为20岁[SD,1岁];32%为女性)运动员检测呈阳性并接受了心脏评估。共有2820名运动员接受了至少一项心脏“三联”检查[12导联心电图(ECG)、肌钙蛋白和/或经胸超声心动图(TTE)],然后在临床上进行了心脏磁共振(CMR)检查。

相比之下,研究人员对198名运动员进行了CMR初筛。ECG(21/2999,0.7%)、心肌肌钙蛋白(24/2719,0.9%)和TTE(24/2556,0.9%)检测发现伴有SARS-CoV-2心脏受累。在21/3018(0.7%)名运动员中确诊了明确的、极可能的或可能发生的SARS-CoV-2心脏受累,其中,15/2820(0.5%)名患者接受了临床指征的CMR检查(n=119),6/198(3.0%)名患者接受了CMR初筛。因此,与初筛CMR(6/198,3.0%)相比,临床指示的CMR(15/119,12.6%)对SARS-COV-2心脏受累的CMR诊断率提高了4.2倍。调整种族和性别后,SARS-CoV-2感染后心脏受累的预测因素包括心肺症状(OR:3.1,95%CI为1.2,7.7)或至少一项异常的三联检查结果(OR:37.4,95%CI为13.3,105.3)。5名(0.2%)运动员因SARS-CoV-2感染的非心脏并发症而需要住院治疗。在临床监测期间(中位随访为113天[IQR=90,146]),有1例(0.03%)患者不良心脏事件可能与SARS-CoV-2感染无关。

由此可见,SARS-CoV-2感染的年轻运动员短期随访中心脏受累患病率和临床事件风险均较低

原始出处:

Nathaniel Moulson,et al.SARS-CoV-2 Cardiac Involvement in Young Competitive Athletes.Circulation. 2021.https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.054824

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1938002, encodeId=23d919380027b, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Wed Nov 03 22:12:00 CST 2021, time=2021-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004599, encodeId=dd4020045999c, content=<a href='/topic/show?id=082d5145e4b' target=_blank style='color:#2F92EE;'>#心脏受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51457, encryptionId=082d5145e4b, topicName=心脏受累)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfab443, createdName=saikp, createdTime=Thu Jun 10 20:12:00 CST 2021, time=2021-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321268, encodeId=933113212687f, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, createdName=小刀医生, createdTime=Tue Apr 20 07:12:00 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604604, encodeId=458d1604604ac, content=<a href='/topic/show?id=88e6941544c' target=_blank style='color:#2F92EE;'>#运动员#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94154, encryptionId=88e6941544c, topicName=运动员)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c1419230799, createdName=gujh, createdTime=Tue Apr 20 07:12:00 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958056, encodeId=d11e958056e9, content=好文章!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Apr 18 17:03:57 CST 2021, time=2021-04-18, status=1, ipAttribution=)]
    2021-11-03 hukaixun
  2. [GetPortalCommentsPageByObjectIdResponse(id=1938002, encodeId=23d919380027b, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Wed Nov 03 22:12:00 CST 2021, time=2021-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004599, encodeId=dd4020045999c, content=<a href='/topic/show?id=082d5145e4b' target=_blank style='color:#2F92EE;'>#心脏受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51457, encryptionId=082d5145e4b, topicName=心脏受累)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfab443, createdName=saikp, createdTime=Thu Jun 10 20:12:00 CST 2021, time=2021-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321268, encodeId=933113212687f, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, createdName=小刀医生, createdTime=Tue Apr 20 07:12:00 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604604, encodeId=458d1604604ac, content=<a href='/topic/show?id=88e6941544c' target=_blank style='color:#2F92EE;'>#运动员#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94154, encryptionId=88e6941544c, topicName=运动员)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c1419230799, createdName=gujh, createdTime=Tue Apr 20 07:12:00 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958056, encodeId=d11e958056e9, content=好文章!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Apr 18 17:03:57 CST 2021, time=2021-04-18, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1938002, encodeId=23d919380027b, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Wed Nov 03 22:12:00 CST 2021, time=2021-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004599, encodeId=dd4020045999c, content=<a href='/topic/show?id=082d5145e4b' target=_blank style='color:#2F92EE;'>#心脏受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51457, encryptionId=082d5145e4b, topicName=心脏受累)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfab443, createdName=saikp, createdTime=Thu Jun 10 20:12:00 CST 2021, time=2021-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321268, encodeId=933113212687f, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, createdName=小刀医生, createdTime=Tue Apr 20 07:12:00 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604604, encodeId=458d1604604ac, content=<a href='/topic/show?id=88e6941544c' target=_blank style='color:#2F92EE;'>#运动员#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94154, encryptionId=88e6941544c, topicName=运动员)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c1419230799, createdName=gujh, createdTime=Tue Apr 20 07:12:00 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958056, encodeId=d11e958056e9, content=好文章!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Apr 18 17:03:57 CST 2021, time=2021-04-18, status=1, ipAttribution=)]
    2021-04-20 小刀医生
  4. [GetPortalCommentsPageByObjectIdResponse(id=1938002, encodeId=23d919380027b, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Wed Nov 03 22:12:00 CST 2021, time=2021-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004599, encodeId=dd4020045999c, content=<a href='/topic/show?id=082d5145e4b' target=_blank style='color:#2F92EE;'>#心脏受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51457, encryptionId=082d5145e4b, topicName=心脏受累)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfab443, createdName=saikp, createdTime=Thu Jun 10 20:12:00 CST 2021, time=2021-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321268, encodeId=933113212687f, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, createdName=小刀医生, createdTime=Tue Apr 20 07:12:00 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604604, encodeId=458d1604604ac, content=<a href='/topic/show?id=88e6941544c' target=_blank style='color:#2F92EE;'>#运动员#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94154, encryptionId=88e6941544c, topicName=运动员)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c1419230799, createdName=gujh, createdTime=Tue Apr 20 07:12:00 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958056, encodeId=d11e958056e9, content=好文章!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Apr 18 17:03:57 CST 2021, time=2021-04-18, status=1, ipAttribution=)]
    2021-04-20 gujh
  5. [GetPortalCommentsPageByObjectIdResponse(id=1938002, encodeId=23d919380027b, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Wed Nov 03 22:12:00 CST 2021, time=2021-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004599, encodeId=dd4020045999c, content=<a href='/topic/show?id=082d5145e4b' target=_blank style='color:#2F92EE;'>#心脏受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51457, encryptionId=082d5145e4b, topicName=心脏受累)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfab443, createdName=saikp, createdTime=Thu Jun 10 20:12:00 CST 2021, time=2021-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321268, encodeId=933113212687f, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, createdName=小刀医生, createdTime=Tue Apr 20 07:12:00 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604604, encodeId=458d1604604ac, content=<a href='/topic/show?id=88e6941544c' target=_blank style='color:#2F92EE;'>#运动员#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94154, encryptionId=88e6941544c, topicName=运动员)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c1419230799, createdName=gujh, createdTime=Tue Apr 20 07:12:00 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958056, encodeId=d11e958056e9, content=好文章!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Apr 18 17:03:57 CST 2021, time=2021-04-18, status=1, ipAttribution=)]
    2021-04-18 jyzxjiangqin

    好文章!

    0

相关资讯

J Rheumatol:中国多发性大动脉炎患者心脏受累的临床特征

伴有心脏异常的TA患者并不罕见,特别是伴Numano V型血管受累的患者。

JAHA:COVID-19患者心脏受累的临床特征和危险因素

COVID-19患者心脏受累很常见。CRP水平升高、老年、潜在合并症和NCP严重程度是COVID-19患者心脏受累的主要危险因素。为了降低死亡率,在COVID-19治疗期间应更加注重心血管保护。