JAHA:代谢综合征状态变化与房颤风险之间的关联

2021-08-09 MedSci原创 MedSci原创

在大规模亚洲人群中,MetS状态的动态变化和持续性MetS与AF风险增加相关。

关于代谢综合征(MetS)状态的变化是否会影响新发房颤(AF)风险的信息很少。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员旨在使用来自全国观察队列的数据评估MetS状态和MetS组分的变化是否影响AF风险。

该研究总共确定了7565531名没有AF的成年人(平均年龄为47±14岁),他们接受了韩国国家健康保险合作组织的2次健康检查。根据连续评估中MetS状态的变化将患者分为4组,如下:持续性MetS患者(n=1388850),第二次评估中新诊断为MetS的健康患者(n=608158),在第二次评估中健康的MetS患者(n=798555)和持续健康的个体(n=4769968)。

在平均7.9年的随访期间,139305(1.8%)名患者被诊断出AF。多变量调整后,持续性MetS患者AF风险升高31%,第二次评估健康的MetS患者AF风险升高26%,第二次评估新诊断为MetS的健康患者AF风险升高16%,相比于持续健康的个体。无论MetS组分类型如何,AF风险都与组分数量的变化相关。与老年组(≥65岁)相比,青年组和中年组(分别为20-39岁和40-64岁)的AF风险与MetS状态变化密切相关。

由此可见,在大规模亚洲人群中,MetS状态的动态变化和持续性MetS与AF风险增加相关。

原始出处:

Seo‐Young Lee.et al.Association Between Change in Metabolic Syndrome Status and Risk of Incident Atrial Fibrillation: A Nationwide Population‐Based Study.JAHA.2021.https://www.ahajournals.org/doi/10.1161/JAHA.121.020901

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    2021-08-11 zhaohui6731
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    2021-08-11 zhouqu_8
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    2021-08-09 心介

    房颤,临床上碰到很多哦

    0

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