DCR:与结肠切除术相比,选择性肠造口术后艰难梭菌感染发生率更高

2018-06-09 MedSci MedSci原创

艰难梭菌感染是由治疗或手术干预后,革兰氏阳性厌氧细菌的增殖引起的,并可导致毒性并发症,再次手术和死亡。本项研究是探讨结肠切除术与肠造口术对于艰难梭菌感染发生率的影响。

背景:  艰难梭菌感染是由治疗或手术干预后,革兰氏阳性厌氧细菌的增殖引起的,并可导致毒性并发症,再次手术和死亡。本项研究是探讨结肠切除术与肠造口术对于艰难梭菌感染发生率的影响。

方法: 本研究采用回顾性数据分析,共有2235名患者接受了选择性造口转流术,而10403名患者接受了选择性结肠切除术。主要观察指标为手术后30天内艰难梭菌感染的发生率。

结果: 肠造口术后30天艰难梭菌感染发生率显着高于结肠切除术(3.04%vs 1.25%; p <0.001)。Logistics回归分析提示造口转流(OR = 2.701(95%CI,1.966-3.711); p <0.001),吸烟(OR = 1.520(95%CI,1.063-2.174); p = 0.022 ),类固醇(OR = 1.677(95%CI,1.005-2.779); p = 0.048),和播散性癌症(OR = 2.312(95%CI,1.437-3.719); p = 0.001)与术后30天内发生艰难梭菌感染有关。

结论: 接受选择性肠造口术的患者术后艰难梭菌感染的发生率远高于接受选择性结肠切除术的患者。

原始出处:

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    2018-06-16 jyzxjiangqin

    选择性肠造口术治疗.

    0

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  7. [GetPortalCommentsPageByObjectIdResponse(id=1877034, encodeId=537818e70349c, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Wed Nov 28 09:34:00 CST 2018, time=2018-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706549, encodeId=7b581e0654938, content=<a href='/topic/show?id=0df2e87477d' target=_blank style='color:#2F92EE;'>#结肠切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78747, encryptionId=0df2e87477d, topicName=结肠切除术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a89f31292094, createdName=12498568m60暂无昵称, createdTime=Sun Jan 13 22:34:00 CST 2019, time=2019-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922907, encodeId=54d3192290efe, content=<a href='/topic/show?id=78f794e800a' target=_blank style='color:#2F92EE;'>#选择性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94780, encryptionId=78f794e800a, topicName=选择性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a0802500050, createdName=肉我只吃一口, createdTime=Fri Aug 17 10:34:00 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826450, encodeId=84c018264508b, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sun May 26 16:34:00 CST 2019, time=2019-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324568, encodeId=426832456829, content=选择性肠造口术治疗., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Jun 16 07:08:16 CST 2018, time=2018-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585226, encodeId=c4b915852268b, content=<a href='/topic/show?id=08aa949e01c' target=_blank style='color:#2F92EE;'>#造口术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94970, encryptionId=08aa949e01c, topicName=造口术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d8b17134701, createdName=wjcjjian, createdTime=Mon Jun 11 13:34:00 CST 2018, time=2018-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=323178, encodeId=49023231e8d7, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Mon Jun 11 05:20:25 CST 2018, time=2018-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=323074, encodeId=2b773230e40d, content=学习了.获益匪浅.感谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Jun 10 14:47:16 CST 2018, time=2018-06-10, status=1, ipAttribution=)]
    2018-06-11 121832a9m88暂无昵称

    学习了

    0

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    2018-06-10 虈亣靌

    学习了.获益匪浅.感谢分享.

    0