2021年10月11日简报:张文宏认为中国最快2022年初将有条件开放!多种哺乳动物可成为新冠宿主;新冠免疫记忆超预期

2021-10-11 MedSci整理 MedSci整理

截至北京时间2021年10月11日7时01分,Worldometers世界实时统计数据显示,全球累计确诊新冠肺炎(COVID-19)病例超过238619万例,新增289,511例,达到238,619,

截至北京时间2021年10月11日7时01分,Worldometers世界实时统计数据显示,全球累计确诊新冠肺炎COVID-19)病例超过238619万例,新增289,511例,达到238,619,712例。累计死亡病例486.6万例,达到4,866,779例。新增死亡为4,364例。康复为215,784,269例,重症和危重症病人达到82,518例;全球新冠确诊病例超过100万例的国家达35个,110个国家病例超10万例。昨日报道:2021年10月10日简报:年底时可能有多款新冠病毒治疗口服药问世;安徽、福建、湖北、黑龙江、海南、广西、浙江、河南等地启动加强针;新西兰正式宣布同新冠共存

巴“核弹之父”感染新冠后离世

10日,被誉为巴基斯坦“核弹之父”的著名核科学家阿卜杜勒·卡迪尔·汗在伊斯兰堡病逝,终年85岁。巴基斯坦国家领导人和各党派政要发文悼念。

阿卜杜勒·卡迪尔·汗今年8月因感染新冠肺炎后送院治疗,数周前获准出院回家,但后来肺部病情恶化再度入院,不幸于10日上午病逝。《华尔街日报》称,据医生透露,阿卜杜勒·卡迪尔·汗死于感染新冠之后出现的呼吸困难。

肺对新冠感染有强烈“免疫记忆”,新研究提示疫苗反应或超预期

人体遭遇新冠病毒后,免疫系统不仅会对抗病毒,还能长时间“记住”它们,从而预防再次感染。这种长期的免疫记忆也是疫苗起保护作用的基础。

在一项新研究中,科学家们在新冠患者的肺部以及肺周围的淋巴结中找到了对新冠感染有长期免疫记忆的直接证据确认新冠感染的免疫记忆对于疫苗接种或加强免疫的设计具有重要的指导意义

这项研究由哥伦比亚大学(Columbia University)免疫学家Donna Farber教授和La Jolla 免疫研究所的病毒学家Shane Crotty教授合作领衔。

研究结果显示,直到感染新冠后的六个月,患者的骨髓、脾、肺和多处淋巴结中依然存在大量记忆CD4阳性T细胞、CD8阳性T细胞和B细胞。其中,肺和肺相关淋巴组织是SARS-CoV-2特异性的记忆B细胞和记忆T细胞分布的最主要部位

在肺相关淋巴结中,研究人员还发现了SARS-CoV-2特异性生发中心B细胞和滤泡辅助性T细胞(Tfh)同时存在,后者可以促进B细胞的分化,而生发中心B细胞的持续存在可以确保抗体在循环系统中长期维持,以及免疫应答的持续存在。

这一系列发现提供了直接的证据表明新冠感染后局部组织建立起长期保护性免疫。

感染时症状越严重,新冠免疫记忆“越深刻”

抵御新冠病毒的攻击后,我们体内的免疫系统能不能“记住”?如果能,感染一次新冠是不是有机会终身免疫?如果不能,那么应该在多久后加强免疫。

新冠病毒感染后人体的免疫记忆问题,始终是应对疫情的焦点。10月5日,中国疾控中心病毒病所刘军研究员联合高福院士、武桂珍研究员团队在权威期刊《临床传染病》(Clinical Infectious Diseases)上发表研究显示,人体对新冠病毒的免疫记忆能够维持一年以上,感染后一年仍然具有新冠特异性中和抗体和T细胞免疫记忆的康复者比例分别为95%和92%。

“我们对101名新冠肺炎康复者进行了半年和一年的回访,通过血清样本的多项检测,包括对活病毒的中和反应,以及免疫记忆T细胞的病毒特异性检测,来探测免疫抗体和免疫记忆T细胞是否还存在。”10月7日,论文通讯作者之一、中国疾控中心病毒病预防控制所研究员刘军告诉科技日报记者。

多种哺乳动物可成为新冠宿主

可被新冠病毒感染的已远不仅是人。

近日,CCDC WEEKLY登出观点文章Perspectives: COVID-19 Expands Its Territories from Humans to Animals,两位作者分别来自中国科学院与中国疾控中心,通讯作者为中国科学院院士、中国疾控中心主任高福。

文章指出,除了人类以外,一些哺乳动物也曾感染新冠。其中既有被圈养的动物,也有野生动物。

其中,动物园中的猫、狗、狮子、老虎、水貂、雪貂,曾通过接触新冠患者而感染。

在人类进行的感染实验中,兔子、猪、狐狸、果子狸等被认为是新冠的可能易感宿主。

自然界中,则发现雪豹、美洲狮和大猩猩感染新冠。

目前已知的新冠宿主图。(A)自然界中已报告感染新冠的物种(B)据报道在感染实验中感染新冠的物种。注:实线箭头表示有明确证据表明新冠的跨物种传播方向,虚线箭头表示可能存在的跨物种传播方向。

东京新增新冠确诊病例82例,创近一年来新低

日本放送协会(NHK)10月9日报道,日本东京都新增82例新冠确诊病例,创去年10月19日以来新低。

张文宏:中国最快2022年初将有条件开放!

在近期的第五届中阿博览会大健康产业论坛暨第三届“互联网+医疗健康”应用大会上。中国工程院院士钟南山和复旦大学附属华山医院感染科主任、国家传染病医学中心主任文宏医生都对疫情现状发表了重要讲话。

张文宏进一步说明:“世界各国有条件地恢复人员往来,今年下半年就会开始。我们希望中国在2022年上半年可以有条件地跟一些国家恢复往来这取决于打疫苗的速度。

继美国之后,巴西成为第二个新冠肺炎死亡人数超60万国家

巴西卫生部10月8日晚6点公布的数据显示,新冠肺炎死亡人数达60.0425万,继美国之后,巴西成为全球第二个新冠肺炎死亡人数超过60万的国家。

中国是首个同巴开展疫苗合作的国家,中国提供的疫苗和原液占巴方接收总量近80%。

据巴西环球电视台10月7日汇集的数据显示,巴西已有9721万人完成了全面接种,占巴西总人口的45.57%。

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    2021-10-11 DR.Fu SIR

    争取早日开放!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1404781, encodeId=edc01404e8139, content=<a href='/topic/show?id=1a4f4649925' target=_blank style='color:#2F92EE;'>#宿主#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46499, encryptionId=1a4f4649925, topicName=宿主)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Tue Oct 12 22:40:17 CST 2021, time=2021-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514042, encodeId=5f2c1514042aa, content=<a href='/topic/show?id=845339961b7' target=_blank style='color:#2F92EE;'>#哺乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39961, encryptionId=845339961b7, topicName=哺乳)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8fd10610597, createdName=ms1065684921169360, createdTime=Tue Oct 12 22:40:17 CST 2021, time=2021-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516760, encodeId=efd51516e6035, content=<a href='/topic/show?id=2ef539962d7' target=_blank style='color:#2F92EE;'>#哺乳动物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39962, encryptionId=2ef539962d7, topicName=哺乳动物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=762011007983, createdName=ms6279672939590805, createdTime=Tue Oct 12 22:40:17 CST 2021, time=2021-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059515, encodeId=e16c10595156f, content=争取早日开放!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=821f2227826, createdName=DR.Fu SIR, createdTime=Mon Oct 11 16:58:53 CST 2021, time=2021-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059343, encodeId=47ab10593433a, content=triple绝命GJ部队里头, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Mon Oct 11 09:21:27 CST 2021, time=2021-10-11, status=1, ipAttribution=)]
    2021-10-11 查查佳佳

    triple绝命GJ部队里头

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