BMC Obesity:病态肥胖患者肠易激综合征的患病率和预测因素研究

2019-03-19 不详 MedSci原创

据报道,肠易激综合征患者在病态肥胖患者中比在一般人群中更常见,然而这种关联的原因目前尚不清楚。本研究的目的是探究病态肥胖患者肠易激综合征和其他功能性肠病的患病率,并寻找肠易激综合征的预测因子。

背景
据报道,肠易激综合征患者在病态肥胖患者中比在一般人群中更常见,然而这种关联的原因目前尚不清楚。本研究的目的是探究病态肥胖患者肠易激综合征和其他功能性肠病的患病率,并寻找肠易激综合征的预测因子。

方法
研究人员在挪威东南部的两个肥胖中心筛选了减肥手术的患者进行研究。功能性肠病的诊断是根据罗马III标准进行的。使用多变量逻辑回归分析肠易激综合征的预测因子。

结果
研究人员纳入了350名受试者进行分析,两个中心的肠易激综合征患病率分别为17/211(8%)和37/139(27%)。高密度脂蛋白(OR 2.10; 95%CI 1.34-3.29),自我报告的精神疾病(OR 2.39; 95%CI 1.12-5.08)是肠易激综合征的独立预测因子。

结论
本项研究结果表明在两个肥胖中心,肠易激综合征的患病率比同一地区的一般人群高三倍。高患病率似乎与饮食差异或脂肪的吸收或代谢改变有关。

原始出处:

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href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Thu Mar 21 03:49:00 CST 2019, time=2019-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431471, encodeId=002814314e158, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Mar 21 03:49:00 CST 2019, time=2019-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461767, encodeId=fe5d1461e67be, content=<a href='/topic/show?id=92c2132003b' target=_blank style='color:#2F92EE;'>#Obesity#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13200, encryptionId=92c2132003b, topicName=Obesity)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45616444603, createdName=lingaifan, createdTime=Thu Mar 21 03:49:00 CST 2019, time=2019-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588362, encodeId=f990158836249, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Thu Mar 21 03:49:00 CST 2019, time=2019-03-21, status=1, ipAttribution=)]
    2019-11-06 zhanglin3079
  5. 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  6. 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  7. 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  8. 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