Acta Paediatr:亚硝酸盐试验阳性是90天以下无源发烧婴儿侵袭性细菌感染的独立危险因素

2020-02-17 不详 网络

本研究究分析了90天以下无源发烧(FWS)婴儿的亚硝酸盐试纸检测阳性与侵袭性细菌感染(IBI)之间的关系。研究人员对一项前瞻性多中心研究的数据进行了二级分析,该研究于2011年10月至2013年9月在19例小儿急诊科中接受了FWS治疗的90岁以下婴儿进行。IBI被定义为血液或脑脊液阳性。结果显示,在我们研究的3401例婴儿中,有766名(22.5%)的试纸尿检为亚硝酸盐或白细胞酯酶阳性,而有270

本研究究分析了90天以下无源发烧(FWS)婴儿的亚硝酸盐试纸检测阳性与侵袭性细菌感染(IBI)之间的关系。

研究人员对一项前瞻性多中心研究的数据进行了二级分析,该研究于2011年10月至2013年9月在19例小儿急诊科中接受了FWS治疗的90岁以下婴儿进行。IBI被定义为血液或脑脊液阳性。

结果显示,在我们研究的3401例婴儿中,有766名(22.5%)的试纸尿检为亚硝酸盐或白细胞酯酶阳性,而有270名(35.2%)的试纸尿液分析仅为亚硝酸盐阳性。总体上,有107位被诊断患有IBI(3.1%)。尿液试纸正常的患者中,IBI患病率为2.2%,如果白细胞酯酶测试结果为阳性,则为4.4%,亚硝酸盐测试为阳性的患者为8.3%,两项测试均为阳性的患者为10.6%。经过多变量分析后,亚硝酸盐检测阳性仍是IBI的独立危险因素(风险比为2.7,95%置信区间为1.4-4.9)。

综上所述,该研究结果表明,在90天以下FWS婴儿中,亚硝酸盐尿试纸试验阳性是IBI的独立危险因素。

原始出处:

Velasco R, Gomez B, et al., A positive nitrite test was an independent risk factor for invasive bacterial infections in infants under 90 days of age with fever without source. Acta Paediatr. 2020 Feb 15. doi: 10.1111/apa.15230.

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    2020-08-30 windight
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2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1376895, encodeId=f98713e689563, content=<a href='/topic/show?id=ddc13e87938' target=_blank style='color:#2F92EE;'>#发烧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37879, encryptionId=ddc13e87938, topicName=发烧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25c8396, createdName=ssnine, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489847, encodeId=7a1e148984e84, content=<a href='/topic/show?id=bcd5204ea9' target=_blank style='color:#2F92EE;'>#AED#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2047, encryptionId=bcd5204ea9, topicName=AED)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a0108610571, createdName=makuansheng, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
    2020-07-11 paperyu
  5. 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2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1376895, encodeId=f98713e689563, content=<a href='/topic/show?id=ddc13e87938' target=_blank style='color:#2F92EE;'>#发烧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37879, encryptionId=ddc13e87938, topicName=发烧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25c8396, createdName=ssnine, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489847, encodeId=7a1e148984e84, content=<a href='/topic/show?id=bcd5204ea9' target=_blank style='color:#2F92EE;'>#AED#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2047, encryptionId=bcd5204ea9, topicName=AED)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a0108610571, createdName=makuansheng, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
  6. 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createdAvatar=null, createdBy=a0108610571, createdName=makuansheng, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
  7. 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2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1376895, encodeId=f98713e689563, content=<a href='/topic/show?id=ddc13e87938' target=_blank style='color:#2F92EE;'>#发烧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37879, encryptionId=ddc13e87938, topicName=发烧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25c8396, createdName=ssnine, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489847, encodeId=7a1e148984e84, content=<a href='/topic/show?id=bcd5204ea9' target=_blank style='color:#2F92EE;'>#AED#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2047, encryptionId=bcd5204ea9, topicName=AED)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a0108610571, createdName=makuansheng, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
    2020-02-19 sunyl07
  8. 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2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1376895, encodeId=f98713e689563, content=<a href='/topic/show?id=ddc13e87938' target=_blank style='color:#2F92EE;'>#发烧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37879, encryptionId=ddc13e87938, topicName=发烧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25c8396, createdName=ssnine, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489847, encodeId=7a1e148984e84, content=<a href='/topic/show?id=bcd5204ea9' target=_blank style='color:#2F92EE;'>#AED#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2047, encryptionId=bcd5204ea9, topicName=AED)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a0108610571, createdName=makuansheng, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
    2020-02-19 ssnine
  9. 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2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1376895, encodeId=f98713e689563, content=<a href='/topic/show?id=ddc13e87938' target=_blank style='color:#2F92EE;'>#发烧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37879, encryptionId=ddc13e87938, topicName=发烧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25c8396, createdName=ssnine, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489847, encodeId=7a1e148984e84, content=<a href='/topic/show?id=bcd5204ea9' target=_blank style='color:#2F92EE;'>#AED#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2047, encryptionId=bcd5204ea9, topicName=AED)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a0108610571, createdName=makuansheng, createdTime=Wed Feb 19 05:07:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
    2020-02-19 makuansheng