2012中国“骨髓增生异常综合征诊疗共识”发布(附下载)

2012-04-25 MedSci 中华血液学杂志

       骨髓增生异常综合征( MDS)是起源于造血干细胞的一组异质性髓系克隆性疾病,特点是髓系细胞发育异常,表现为无效造血、难治性血细胞减少、造血功能衰竭,高风险向急性髓系白血病(AML)转化。为规范临床诊治,中华医学会血液分会组织相关专家,讨论完成2012年《骨髓增生异常综合征诊断与治疗专家共识》,该共识发表在最新一期的《中华血液学杂志》上。 &n

       骨髓增生异常综合征( MDS)是起源于造血干细胞的一组异质性髓系克隆性疾病,特点是髓系细胞发育异常,表现为无效造血、难治性血细胞减少、造血功能衰竭,高风险向急性髓系白血病(AML)转化。为规范临床诊治,中华医学会血液分会组织相关专家,讨论完成2012年《骨髓增生异常综合征诊断与治疗专家共识》,该共识发表在最新一期的《中华血液学杂志》上。
 
 
       中国医学科学院血液病研究所的肖志坚,上海交通大学附属瑞金医院的沈志祥,浙江大学附属第一医院金洁,天津医科大学总医院邵宗鸿,解放军总医院于力,哈尔滨血液病肿瘤研究所马军,北京大学人民医院黄晓军等教授参与了共识讨论。
 
       共识包含2部分,第一部分诊断与分型,第二部分预后分组与治疗。诊断分型部分给出了MDS诊断流程、标准、鉴别诊断及诊断的分型等内容。在预后分组与治疗部分则重点讨论了MDS的治疗方案,包括支持治疗、免疫抑制治疗、免疫调节治疗、表观遗传学修饰治疗、细胞毒性治疗及血干细胞移植。

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