Tobacco Control :这...研究表明接触二手烟的人口腔癌风险增加51%

2021-04-30 “生物世界”公众号 “生物世界”公众号

口腔癌(Oral cancer),是发生在口腔的恶性肿瘤之总称,每年在全球造成超过44万例新发病例和超过22万死亡病例。

口腔癌(Oral cancer),是发生在口腔的恶性肿瘤之总称,每年在全球造成超过44万例新发病例和超过22万死亡病例。

口腔癌的重要危险因素包括:吸烟、饮酒和咀嚼槟榔。吸烟导致的烟草烟雾是人类最大的化学致癌物接触源,它导致世界上40%的癌症相关死亡。

然而,不仅吸烟者受到这种影响,许多不吸烟的人同样受到影响,根据来自192个国家的数据,33%的男性不吸烟者、35%的女性不吸烟者,以及40%的儿童因被动接触二手烟而吸入烟草烟雾。

先前的研究表明,接触二手烟会导致多种疾病,包括肺癌。尽管已知吸烟是引起口腔癌的原因,但尚未确定二手烟是否也会引起口腔癌。

近日,来自葡萄牙、英国、西班牙和美国的国际研究团队在 BMJ 旗下 Tobacco Control 期刊发表了题为:Secondhand smoke exposure and oral cancer risk: a systematic review and meta-analysis 的论文。

该论文回顾并分析了五项已在亚洲、欧洲、北美和拉丁美洲进行相关研究,涉及6977人,其中3452人接触了二手烟,而3525人未接触二手烟。发现接触二手烟的人患口腔癌的风险高出51%。此外,与未接触二手烟者相比,接触二手烟持续时间超过10年或15年,会使患口腔癌的风险增加两倍以上。

研究团队认为,这项系统审查和荟萃分析支持二手烟暴露与口腔癌之间的因果关系。此外,对二手烟暴露反应的分析,包括对二手烟暴露持续时间(超过10年或15年)的分析,进一步支持了这一因果推断。

研究团队还表示,这项研究增加了对二手烟暴露危害的认识,为公共卫生专业人员,研究人员和政策制定者制定并提供有效的二手烟暴露预防计划提供了指。

原始出处:

Lorena C. Mariano, et al. Secondhand smoke exposure and oral cancer risk: a systematic review and?meta-analysis. Tob Control 2021;0:1–11. doi:10.1136/tobaccocontrol-2020-056393.

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    2021-09-07 sjq027
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    2021-12-22 lsj628
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    2021-04-29 仁者大医
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