Hyleukin-7(NT-I7)联合Pembrolizumab治疗复发难治晚期实体瘤:美国FDA已批准IND申请

2020-01-28 Allan MedSci原创

生物制药公司NeoImmuneTech近日宣布,美国FDA批准了Hyleukin-7(NT- I7)联合默克公司的抗PD-1抗体(Pembrolizumab)治疗复发/难治性(R/R)晚期实体瘤患者。该IND的获准使得NeoImmuneTech可以启动Ib/IIa期临床研究。

生物制药公司NeoImmuneTech近日宣布,美国FDA批准了Hyleukin-7NT- I7)联合默克公司的抗PD-1抗体(Pembrolizumab)治疗复发/难治性(R/R)晚期实体瘤患者。该IND的获准使得NeoImmuneTech可以启动Ib/IIa临床研究。

NeoImmuneTech的首席医学官称:作为一家公司,我们正在努力为患有R / R晚期实体瘤的患者,包括那些对检查点抑制剂(CPI)单药治疗无效的患者开发安全有效的免疫疗法


原始出处:

https://www.firstwordpharma.com/node/1696350?tsid=4

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    2020-03-26 feather89
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    2020-12-26 snf701207
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    2020-03-08 chendoc242
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    2020-01-30 1478fa69m73暂无昵称

    学习了

    0

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    2020-01-30 xiaogang319
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SYNB1891与PD-L1检查点抑制剂联合治疗晚期实体瘤

Synlogic制药公司近日宣布,将与罗氏制药开展新的临床合作,以探索Synlogic的SYNB1891(一种双重免疫激活剂)与罗氏制药的PD-L1检测点抑制剂atezolizumab联合用于晚期实体瘤的有效性和安全性。Synlogic预计将于2019年下半年向FDA提交SYNB1891的研究性新药申请(IND)。

Alkermes开始验证ALKS 4230治疗晚期实体瘤的有效性

Alkermes公司近日宣布启动ARTISTRY-2试验,这是一项新的针对候选药物ALKS 4230的临床研究。ARTISTRY-2试验将评估ALKS 4230单药皮下注射及与PD-1抑制剂KEYTRUDA®(pembrolizumab)联合使用治疗晚期实体瘤患者的有效性和安全性。