Nutrition :营养不良提示心脏手术患者预后差!

2020-12-30 MedSci原创 MedSci原创

营养物质是生命活动的物质基础,是维持生命体正常运转不可缺少的能量物质。近期Nutrition杂志发表的一项研究表示,患者的营养状况对预后影响显著。营养不足的程度越高,预后越差,尤其是心脏瓣膜病患者。

营养物质是生命活动的物质基础,是维持生命体正常运转不可缺少的能量物质。营养物质包括糖类、脂类、蛋白质、维生素、无机盐、水和膳食纤维等,经过新陈代谢转化为构成维持生命活动的能量。正常人体所需的营养摄入不足则导致营养不良。随着现代医学的发展,科学家们将更多的目光聚焦在患者营养不良的问题,尤其是接受心脏手术的患者。

近日,发表在Nutrition杂志的一项研究发现,患者的营养状况对预后影响显著。营养不足的程度越高,预后越差,对于心脏瓣膜病患者该相关性更为显著。

研究人员收纳了来自201111日至20118311187名接受过心脏手术的患者,平均年龄为58.86±10.07 岁,中位随访时间为73.4 个月。通过营养筛查工具收集患者营养健康数据,包括营养不良通用筛查工具(MUST),短期营养评估问卷(SNAQ),迷你营养评估(MNA)以及营养风险筛查2002(NRS-2002)。另外,研究人员还收集了患者术前,术中和术后的数据,包括术中心肺分流术 CPB)时间和术后特征(如术后并发症、ICU天数和住院时间等),以评估基线营养不良与心脏手术后长期生存率之间的关系。在随访1年、3年和8年后,研究人员分别打电话询问患者健康状况。

结果显示,在随访中,有37.8%的患者没有获得随访机会。在剩下的患者中,有营养不良风险和无营养不良风险的患者 8年总体生存率分别为68%77%。对心脏瓣膜病患者进行3年随访,营养不良患者生存率与无营养不良患者有显著差异(83% VS 93%)。此外,多变量Cox回归模型显示,心肺分流时间小于110.5分钟,术前白蛋白和C反应蛋白是3年生存率的独立预测因子

营养不良对患者的预后的影响

研究人员表示,通过这项研究,我们发现营养健康状况对预后有着重要的价值。希望能通过更多的研究继续寻找改善营养不良患者的解决方案,尤其是心脏外科手术中各种有效的临床营养配方。

原始出处

Sergey M. Efremov et al, Effects of malnutrition on long-term survival in adult patients after elective cardiac surgery, Nutrition (2020). 

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    2020-12-30 Jessica

    营养不足的程度越高,预后越差,对于心脏瓣膜病患者该相关性更为显著。

    0

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    2020-12-30 rayms

    普通人营养不良也不好

    0

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    2020-12-30 124764c3m24(暂无昵称)

    这个可以

    0

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