JAAD:运动对皮肤老化、皮肤癌、银屑病、静脉性溃疡和雄激素性脱发的影响

2021-11-05 医路坦克 MedSci原创

 该文利用PubMed数据库,研究运动对皮肤老化、皮肤癌、银屑病、静脉性腿部溃疡和雄激素性脱发(AGA的)相关影响。

   

      虽然大部分人都赞同适量的运动可以提供健康益处,但与皮肤健康相关的好处却鲜为人知。该研究的目的是回顾研究运动在各种皮肤病中的预防和治疗作用的论文。确定是否有足够的数据来推荐对每一种已确定的皮肤病进行锻炼。

     利用PubMed数据库,搜索了2021年1月之前发表的报道与锻炼相关的皮肤结果的文章。确定了研究运动对皮肤老化、皮肤癌、银屑病、静脉性腿部溃疡和雄激素性脱发(AGA)影响的文章。尽管关于运动和痤疮等疾病之间的联系的信念可能存在,但没有发现这样的研究。

     有文献表明可以运动延缓皮肤老化、预防银屑病和改善腿部静脉性溃疡,这就足以建议人们针对这些情况进行锻炼。有规律的运动(每周4小时的高强度有氧运动)与久坐不动的对照组(每周1小时的高强度有氧运动)相比,在控制阳光暴露的情况下,患者角质层的厚度减少。

     此外,剧烈运动,特别是有氧运动和健美操,与降低美国女性患银屑病的风险独立相关。进行每周剧烈运动(相当于跑步105分钟)可使患银屑病的风险降低25%-30%。据推测,运动可降低导致银屑病发病机制的促炎细胞因子水平。最后,虽然各种研究表明,运动可以提高静脉性腿部溃疡的愈合率,但渐进式阻力运动(脚后跟抬高)与规定的体育活动(每周步行30分钟,每周3天)相结合被发现是最有效的。

     目前预防皮肤癌和治疗AGA的证据不足以建议对这些情况进行锻炼。尽管经常运动可以保护皮肤免受自由基的伤害,但持续时间或强度极大的不规律耐力训练,加上缺乏训练,实际上可能会介导氧化应激,并导致皮肤癌。

      运动不仅会增加雄激素的释放,而且还会产生氧化应激,这可能会增加双氢睾酮进入真皮乳头细胞,导致AGA患者脱发。尽管运动实际上可能对AGA患者产生有害影响,但其因果关系尚不确定。需要更严格的研究来阐明运动对这些皮肤病和其他皮肤病的影响。

   希望该文章能够帮助临床医生阐明锻炼对解决特定皮肤病的重要性。这将使患者能够更好地控制自己的健康并改善生活质量。

文献来源:Yeh C,Flatley E,  Elkattawy O, Exercise in Dermatology: Exercise's influence on skin aging, skin cancer, psoriasis, venous ulcers, and androgenetic alopecia.J Am Acad Dermatol 2021 Jul 21;

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    2022-05-20 fusion
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    2021-11-06 小白努力长高高

    很详细的讲解,谢谢

    1

    展开1条回复
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