SMILE术后迟发性弥漫性板层角膜炎合并角膜层间空泡症一例

2018-01-22 佚名 中华眼视光学与视觉科学杂志

患者,男,20岁

【一般资料】

患者,男,20岁

【主诉】

2016年4月12日于我院行双眼飞秒激光小切口角膜基质透镜取出术(SMILE)。

【体格检查】

右眼:-3.75-0.50×170,左眼:-4.00-0.50×10,双眼矫正视力均为0LogMAR。眼压:右眼22mmHg(1mmHg=0.133kPa),左眼21mmHg。A超测角膜厚度:右眼593μm,左眼600μm。

【辅助检查】

双眼眼底检查示视盘色正界清,杯/盘比(C/D)约0.3。术中使用VisuMax飞秒激光仪,频率500kHz,治疗切口位于角膜上方90。,帽厚130μm,透镜厚度右眼97μm,左眼101μm。手术过程双眼激光扫描30S,透镜分离取出顺利。术后第1天复查视力,双眼均为0LogMAR。嘱患者0.1%氟米龙滴眼液4次/d滴眼。术后1周复查,双眼视力-0.1LogMAR,电脑验光:右眼:+0.25,左眼:+0.5-0.5×110。患者术后1个月突感左眼视力下降来诊,复查视力:右眼:-0.1LogMAR,左眼:0.1LogMAR。电脑验光:右眼:-0.25x90,左眼:+1.25-0.75×95。眼压:右眼:14mmHg,左眼:16mmHg。地形图检查正常。眼前节裂隙灯显微镜检查:左眼角膜切口位正,角膜层间弥漫性、细沙状混浊,上方切口附近可见散在气泡,余未见明显异常(见图1A)。双眼角膜内皮细胞计数均正常。眼前节光学相干断层扫描(OCT)检查示右眼正常,左眼可见角膜层间高反射影像,部分切面可见无反射层间空泡(见图2A)。



【初步诊断

左眼弥漫性板层角膜炎Ⅱ级合并角膜层间空泡症,双眼SMILE术后。

【治疗】

给予左眼0.1%氟米龙6次/d滴眼.双眼噻吗心安滴眼液2次/d滴眼,1周后复查,双眼视力均为-0.1LogMAR。电脑验光:右眼:-0.25,左眼:+1.00-0.50×90。眼压:右眼:14mmHg,左眼:15mmHg。眼前节裂隙灯显微镜检查:左眼角膜层间混浊明显减轻,其间空泡仍然可见。嘱患者逐渐停用0.1%氟米龙及噻吗心安滴眼液。后继续观察数周,双眼视力稳定。术后1个月眼前节裂隙灯显微镜检查:左眼角膜透亮,上方切口附近原散在气泡处角膜层间局限性混浊(见图1B),左眼OCT检查:原空泡消失变小.基质层间混浊局限性存在(见图2B)。


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    2018-01-24 snowpeakxu
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    2018-01-22 hhh678

    henhao

    0

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    2018-01-22 惠映实验室

    学习了.谢谢.

    0

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