BMJ:pH1N1流感疫苗新生儿安全性研究

2019-07-11 MedSci MedSci原创

研究认为, pH1N1流感疫苗对孕妇及新生儿是安全的

近日研究人员就2009 H1N1流感(pH1N1)孕期疫苗接种与幼儿健康不良事件之间的相关性进行了考察。

2009-10年间总计10249名新生儿,随访至5岁。研究的主要终点为免疫相关疾病(传染病,哮喘),非免疫相关疾病(肿瘤,感觉障碍)和非特定疾病(紧急或住院医疗,儿科复杂的慢性疾病)的发病率。

31295名(30%)新生儿宫内pH1N1疫苗暴露。组间上下呼吸道感染、中耳炎、任何传染病、肿瘤、感觉障碍、紧急和住院保健服务、儿童复杂的慢性疾病或死亡率差异不显著。宫内pH1N1疫苗暴露与哮喘(1.05)发病率略微升高以及感染(0.94)发病率略微下降相关。

研究认为, pH1N1流感疫苗对孕妇及新生儿是安全的。

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    2020-01-29 gaoxiaoe
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    2019-07-13 TZF0806
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