Food Chem:甜味蛋白质brazzein的抗氧化、抗炎和抗过敏活性

2018-06-25 MedSci MedSci原创

甜味蛋白质可用作食品、饮料和药品中的低热量糖代用品。Brazzein是一种有吸引力的甜味剂,因为其甜度高,与糖的味道类似,并且在高温和宽pH范围内具有良好的稳定性。为了研究brazzein的生物活性,研究人员在体外测定了其抗菌、抗真菌、抗氧化、抗炎和抗过敏活性。 结果显示,brazzein没有显示出抗菌和抗真菌活性,尽管它与具有抗菌作用的防御素和具有抗真菌作用的drosomycin显示出约45%或

甜味蛋白质可用作食品、饮料和药品中的低热量糖代用品。Brazzein是一种有吸引力的甜味剂,因为其甜度高,与糖的味道类似,并且在高温和宽pH范围内具有良好的稳定性。为了研究brazzein的生物活性,研究人员在体外测定了其抗菌、抗真菌、抗氧化、抗炎和抗过敏活性。

结果显示,brazzein没有显示出抗菌和抗真菌活性,尽管它与具有抗菌作用的防御素和具有抗真菌作用的drosomycin显示出约45%或更高的相似性。然而,brazzein表现出较强的抗氧化作用,表现出ABTS自由基清除活性(IC50 =12.55μM)和DPPH活性(IC50>30μM)。 此外,Brazzein在β-氨基己糖苷酶测定(IC50>15μM)和环氧合酶-2抑制测定(IC50 =12.62μM)中还分别显示出抗炎活性和抗过敏活性。

综上所述,该研究结果表明,brazzein具有抗氧化、抗炎和抗过敏活性,并且作为功能性甜味剂具有巨大的潜力。

原始出处:


Chung JH, Kong JN, Choi HE, Kong KH. Antioxidant, anti-inflammatory, and anti-allergic activities of the sweet-tasting protein brazzein. Food Chem. 2018 Nov 30;267:163-169. doi: 10.1016/j.foodchem.2017.06.084. Epub 2017 Jun 15.

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  6. [GetPortalCommentsPageByObjectIdResponse(id=2049577, encodeId=d42d20495e749, content=<a href='/topic/show?id=264555e961a' target=_blank style='color:#2F92EE;'>#抗过敏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55796, encryptionId=264555e961a, topicName=抗过敏)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a7b6284, createdName=FukaiBao, createdTime=Sun Jul 22 11:52:00 CST 2018, time=2018-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765725, encodeId=a4c31e65725de, content=<a href='/topic/show?id=252ae1803a3' target=_blank style='color:#2F92EE;'>#白质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71803, encryptionId=252ae1803a3, topicName=白质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Tue Aug 14 19:52:00 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1714787, encodeId=4bc31e147874c, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Jul 22 09:52:00 CST 2018, time=2018-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1715584, encodeId=b3d61e1558487, content=<a href='/topic/show?id=a217e58972' target=_blank style='color:#2F92EE;'>#food#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7589, encryptionId=a217e58972, topicName=food)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=68d031960225, createdName=ms6747015003810650, createdTime=Sun Oct 28 09:52:00 CST 2018, time=2018-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1297043, encodeId=6344129e0434e, content=<a href='/topic/show?id=158288e017c' target=_blank style='color:#2F92EE;'>#蛋白质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88701, encryptionId=158288e017c, topicName=蛋白质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Jun 27 09:52:00 CST 2018, time=2018-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326955, encodeId=6e9932695544, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Mon Jun 25 19:00:32 CST 2018, time=2018-06-25, status=1, ipAttribution=)]
    2018-06-25 惠映实验室

    学习了.谢谢分享.

    0