Environmental Research :空气污染让孩子焦虑

2019-05-27 xujing 中国循环杂志

暴露于空气污染是一个公认的全球健康问题,与哮喘等呼吸系统疾病、心脏病和中风风险增加有关,根据世界卫生组织的数据,每年有数百万人死于空气污染。 《环境研究》杂志发表的新证据表明,空气污染也可能影响儿童的代谢和神经发育。


暴露于空气污染是一个公认的全球健康问题,与哮喘等呼吸系统疾病、心脏病和中风风险增加有关,根据世界卫生组织的数据,每年有数百万人死于空气污染。

《环境研究》杂志发表的新证据表明,空气污染也可能影响儿童的代谢和神经发育。

美国辛辛那提大学和辛辛那提儿童医院医学中心的研究人员通过研究青少年前期的神经化学变化,研究了交通相关空气污染与儿童焦虑之间的关系。

研究者指出,最近的证据表明中枢神经系统特别容易受到空气污染影响,这表明它在诸如焦虑或抑郁等精神疾病的病因中起着一定的作用。

该研究是首个使用神经影像学来评估交通相关空气污染暴露、大脑中代谢物失调和健康儿童的焦虑症状的研究。

研究纳入145名12岁的儿童,通过一种专门的核磁共振技术,即磁共振波谱,来观察大脑中的肌醇水平。

肌醇是一种自然产生的代谢物,主要存在于胶质细胞中,有助于维持脑细胞体积和体液平衡,并作为体内激素和胰岛素的调节器。肌醇水平的增加与胶质细胞数量的增加有关,而胶质细胞通常出现在炎症状态。

他们发现,近期暴露于高水平交通相关空气污染的儿童与暴露于较低水平的儿童相比,大脑中的肌醇显著增加。

他们还观察到肌醇增加与焦虑症状相关,最近暴露于高水平交通相关空气污染的儿童的焦虑症状增加了12%。

然而,研究者指出,在这一处于发育阶段的儿童队列中所观察到的焦虑症状的增加相对较小,不太可能导致焦虑症的临床诊断。然而这会对人口健康产生更大的影响,因为空气污染的增加会引发大脑的炎症反应。

原始出处:

Kelly J. Brunst et al, Myo-inositol mediates the effects of traffic-related air pollution ongeneralized anxiety symptoms at age 12? years, Environmental Research (2019). DOI: 10.1016/j.envres.2019.05.009.

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    2020-01-03 lixiaol
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    2019-05-29 july_979
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    2019-05-29 yangshch
  7. [GetPortalCommentsPageByObjectIdResponse(id=1951997, encodeId=9608195199eb5, content=<a href='/topic/show?id=04fa11552da' target=_blank style='color:#2F92EE;'>#Mental#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11552, encryptionId=04fa11552da, topicName=Mental)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Fri Jan 03 03:05:00 CST 2020, time=2020-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1785727, encodeId=a9471e85727cd, content=<a href='/topic/show?id=3cf3682845' target=_blank style='color:#2F92EE;'>#Environmental#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6828, encryptionId=3cf3682845, topicName=Environmental)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Thu Apr 16 14:05:00 CST 2020, time=2020-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1785698, encodeId=1be91e85698e6, content=<a href='/topic/show?id=9855682e90' target=_blank style='color:#2F92EE;'>#environment#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6827, encryptionId=9855682e90, topicName=environment)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/xkicoVBAnV4HxvdCqC1viaW8wdLQdN9hVP9icgqqDsxC6UVPjfhogdfc2iaU1xNUMVlFl5QicicWrjWQBTsVye5ngOQQ/132, createdBy=f92f2500185, createdName=ms7405317358118777, createdTime=Tue May 28 10:05:00 CST 2019, time=2019-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472643, encodeId=470f14e26436e, content=<a href='/topic/show?id=ba4a6436107' target=_blank style='color:#2F92EE;'>#污染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64361, encryptionId=ba4a6436107, topicName=污染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dfe67217539, createdName=小刀医生, createdTime=Wed May 29 06:05:00 CST 2019, time=2019-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1524286, encodeId=75791524286e6, content=<a href='/topic/show?id=053710045ad' target=_blank style='color:#2F92EE;'>#iron#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10045, encryptionId=053710045ad, topicName=iron)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3f1b11597510, createdName=july_979, createdTime=Wed May 29 06:05:00 CST 2019, time=2019-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1557800, encodeId=b95f155e8005d, content=<a href='/topic/show?id=d2601533982' target=_blank style='color:#2F92EE;'>#Research#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15339, encryptionId=d2601533982, topicName=Research)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96ab14929432, createdName=yangshch, createdTime=Wed May 29 06:05:00 CST 2019, time=2019-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=366913, encodeId=44d236691308, content=非常好推荐阅读, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=650f104372, createdName=gcwu82, createdTime=Tue May 28 10:35:04 CST 2019, time=2019-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050495, encodeId=8e611050495f1, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Mon May 27 18:05:00 CST 2019, time=2019-05-27, status=1, ipAttribution=)]
    2019-05-28 gcwu82

    非常好推荐阅读

    0

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    2019-05-27 明天jing

    焦虑是当年年轻人的共同问题,需要认真对待。

    0

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