NEJM:腿部压迫对预防蜂窝织炎复发有益

2020-08-13 MedSci原创 MedSci原创

腿部压迫治疗对降低蜂窝织炎复发有益,但本次研究规模较小且未进行双盲分组,需要进一步的研究证实

腿部慢性水肿是蜂窝织炎的危险因素,为了防止蜂窝织炎复发,患者常常使用腿部穿紧身裤进行腿部压迫治疗,但其有效性尚未得到研究证实。
 
 
近日研究人员开展单中心、随机、非盲试验,慢性腿部水肿和复发性蜂窝织炎患者,在蜂窝织炎预防教育基础上,随机接受腿部压迫治疗(压迫组)或对照。随访每6个月进行一次,持续3年或总计出现45人次蜂窝织炎复发。研究的主要结果是蜂窝织炎复发,对照组中有蜂窝织炎复发的参与者转入压迫组。次要的结果包括蜂窝织炎相关的入院和生活质量评估。
 
84名患者参与研究,41名接受压迫治疗,43名接受对照。临时分析中,总计发生23人次蜂窝组织炎时,压迫治疗组6名参与者(15%),对照组17名参与者(40%)发生蜂窝组织炎(HR=0.23,相对风险[事后分析] 为0.37) ,试验就此终止。
蜂窝组织炎复发率比较
压迫治疗组3例(7%),对照组6例(14%)患者因蜂窝组织炎住院(危险比0.389)。 组间生活质量无显著差异,未发生不良事件。
 
研究认为,腿部压迫治疗对降低蜂窝织炎复发有益,但本次研究规模较小且未进行双盲分组,需要进一步的研究证实。
 
原始出处:
 
Elizabeth Webb et al. Compression Therapy to Prevent Recurrent Cellulitis of the Leg. N Engl J Med, August 13, 2020.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=808649, encodeId=2da98086491b, content=<a href='/topic/show?id=b731888020f' target=_blank style='color:#2F92EE;'>#蜂窝织炎#</a>小病,简易方法,照样能发表NEJM,牛牛!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88802, encryptionId=b731888020f, topicName=蜂窝织炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Aug 13 23:35:18 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035381, encodeId=3467103538152, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Aug 13 22:25:21 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808585, encodeId=149680858578, content=<a href='/topic/show?id=4041126241e' target=_blank style='color:#2F92EE;'>#NEJM#</a> 感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=7, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12624, encryptionId=4041126241e, topicName=NEJM)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=志明, createdTime=Thu Aug 13 22:12:51 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808531, encodeId=e642808531ee, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4535410792, createdName=ms9000000627013470, createdTime=Thu Aug 13 20:40:18 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808520, encodeId=a72f80852012, content=腿部压迫治疗对降低蜂窝织炎复发有益,但本次研究规模较小且未进行双盲分组,需要进一步的研究证实。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Thu Aug 13 19:43:53 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
    2020-08-13 lovetcm

    #蜂窝织炎#小病,简易方法,照样能发表NEJM,牛牛!!

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=808649, encodeId=2da98086491b, content=<a href='/topic/show?id=b731888020f' target=_blank style='color:#2F92EE;'>#蜂窝织炎#</a>小病,简易方法,照样能发表NEJM,牛牛!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88802, encryptionId=b731888020f, topicName=蜂窝织炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Aug 13 23:35:18 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035381, encodeId=3467103538152, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Aug 13 22:25:21 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808585, encodeId=149680858578, content=<a href='/topic/show?id=4041126241e' target=_blank style='color:#2F92EE;'>#NEJM#</a> 感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=7, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12624, encryptionId=4041126241e, topicName=NEJM)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=志明, createdTime=Thu Aug 13 22:12:51 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808531, encodeId=e642808531ee, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4535410792, createdName=ms9000000627013470, createdTime=Thu Aug 13 20:40:18 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808520, encodeId=a72f80852012, content=腿部压迫治疗对降低蜂窝织炎复发有益,但本次研究规模较小且未进行双盲分组,需要进一步的研究证实。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Thu Aug 13 19:43:53 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
    2020-08-13 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=808649, encodeId=2da98086491b, content=<a href='/topic/show?id=b731888020f' target=_blank style='color:#2F92EE;'>#蜂窝织炎#</a>小病,简易方法,照样能发表NEJM,牛牛!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88802, encryptionId=b731888020f, topicName=蜂窝织炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Aug 13 23:35:18 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035381, encodeId=3467103538152, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Aug 13 22:25:21 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808585, encodeId=149680858578, content=<a href='/topic/show?id=4041126241e' target=_blank style='color:#2F92EE;'>#NEJM#</a> 感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=7, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12624, encryptionId=4041126241e, topicName=NEJM)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=志明, createdTime=Thu Aug 13 22:12:51 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808531, encodeId=e642808531ee, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4535410792, createdName=ms9000000627013470, createdTime=Thu Aug 13 20:40:18 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808520, encodeId=a72f80852012, content=腿部压迫治疗对降低蜂窝织炎复发有益,但本次研究规模较小且未进行双盲分组,需要进一步的研究证实。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Thu Aug 13 19:43:53 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
    2020-08-13 志明

    #NEJM# 感谢分享

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=808649, encodeId=2da98086491b, content=<a href='/topic/show?id=b731888020f' target=_blank style='color:#2F92EE;'>#蜂窝织炎#</a>小病,简易方法,照样能发表NEJM,牛牛!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88802, encryptionId=b731888020f, topicName=蜂窝织炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Aug 13 23:35:18 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035381, encodeId=3467103538152, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Aug 13 22:25:21 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808585, encodeId=149680858578, content=<a href='/topic/show?id=4041126241e' target=_blank style='color:#2F92EE;'>#NEJM#</a> 感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=7, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12624, encryptionId=4041126241e, topicName=NEJM)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=志明, createdTime=Thu Aug 13 22:12:51 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808531, encodeId=e642808531ee, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4535410792, createdName=ms9000000627013470, createdTime=Thu Aug 13 20:40:18 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808520, encodeId=a72f80852012, content=腿部压迫治疗对降低蜂窝织炎复发有益,但本次研究规模较小且未进行双盲分组,需要进一步的研究证实。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Thu Aug 13 19:43:53 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=808649, encodeId=2da98086491b, content=<a href='/topic/show?id=b731888020f' target=_blank style='color:#2F92EE;'>#蜂窝织炎#</a>小病,简易方法,照样能发表NEJM,牛牛!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88802, encryptionId=b731888020f, topicName=蜂窝织炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Aug 13 23:35:18 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035381, encodeId=3467103538152, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Aug 13 22:25:21 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808585, encodeId=149680858578, content=<a href='/topic/show?id=4041126241e' target=_blank style='color:#2F92EE;'>#NEJM#</a> 感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=7, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12624, encryptionId=4041126241e, topicName=NEJM)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=志明, createdTime=Thu Aug 13 22:12:51 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808531, encodeId=e642808531ee, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4535410792, createdName=ms9000000627013470, createdTime=Thu Aug 13 20:40:18 CST 2020, time=2020-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808520, encodeId=a72f80852012, content=腿部压迫治疗对降低蜂窝织炎复发有益,但本次研究规模较小且未进行双盲分组,需要进一步的研究证实。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Thu Aug 13 19:43:53 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
    2020-08-13 神盾医疗局局长Jack

    腿部压迫治疗对降低蜂窝织炎复发有益,但本次研究规模较小且未进行双盲分组,需要进一步的研究证实。

    0

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