ARCH PATHOL LAB MED:前列腺癌根治术的三级报告实践模式:对一大批有经验的泌尿外科病理学家的调查

2020-04-05 MedSci原创 MedSci原创

在前列腺癌中,“三级”高分级模式(TPs)与前列腺根治性切除术后的生化复发有关。本研究试图确定TPs的定义和应用方面的差异。

在前列腺癌中,“三级”高分级模式(TPs)与前列腺根治性切除术后的生化复发有关。本研究试图确定TPs的定义和应用方面的差异。

研究人员对105名经验丰富的泌尿外科病理学家进行了关于TPs分级方案的在线调查。研究显示,95名受访者中,有40人(42%)将TPs定义为“第三常见模式”,55人(58%)将TPs定义为“肿瘤的轻微模式/少于5%”。“在模式3和小于5%模式4的肿瘤中,95名受访者中,35名(37%)认为3 + 3 = 6与TP4有关,而56名(59%)认为3 + 4 = 7与TP4有关。”在模式4和小于5%模式5的肿瘤中,在95名受访者中,51人(54%)认为模式4 + 4 = 8与TP5有关,而43人(45%)认为模式4 + 5 = 9。给出了6个场景,其中最常见的模式的顺序是3、4和5(组1)或4、3和5(组2),百分比各不相同。在两组中,当模式5小于5%时,发现98%和93%的受访者会将3 + 4 = 7或4 + 3 = 7分配给TP5。在模式5为15%或25%的情况下,大多数受访者(分别为70%和80%)会将模式5包括在内,即3 + 5 = 8(第1组)或4 + 5 = 9( 组2)。 对于95中的85(89%),TP不会影响组的分配。

这项调查表明在根治性前列腺切除术标本中“三级”分级的定义和应用方面实践模式的巨大差异。在3 + 4 = 7/4 + 3 = 7个模式下观察到一致性较高。这些发现应该为今后评估“三级”模式的标准化和预测价值的研究提供参考。

原始出处:

Samson W. Fine, MD; Debra L. Meisels, BA; Practice Patterns in Reporting Tertiary Grades at Radical Prostatectomy: Survey of a Large Group of Experienced Urologic Pathologists

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    2020-11-26 yb6560
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    2020-04-07 jktdtl
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    2020-04-07 jeanqiuqiu
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    2020-04-07 智慧医人
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    2020-04-05 misszhang

    前列腺癌相关研究,学习了,谢谢梅斯

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