Sci Rep:公路运输工作者患癌风险更高

2021-01-03 MedSci原创 MedSci原创

众所周知,职业病与癌症息息相关。煤矿、石油、化工以及钢铁等工作者患肺癌风险较高,对于司机来说,由于长期接触汽车发动机废气可能会引起代谢系统紊乱,甚至导致多种癌症的发生。

众所周知,职业病与癌症息息相关。煤矿、石油、化工以及钢铁等工作者患肺癌风险较高,对于司机来说,由于长期接触汽车发动机废气可能会引起代谢系统紊乱,甚至导致多种癌症的发生。汽车发动机废气是一种复杂的微粒和气体混合物,包括各种碳氢化合物和衍生物(如苯、甲醛、甲苯和二氧化硫)、无机硫酸盐和硝酸盐、金属(包括铅和铂)以及多环芳烃(PAHs)等。2012年,国际癌症研究机构(IARC)将柴油发动机废气列为致癌物,确认了其对肺癌的致癌性,并报告了其与膀胱癌的积极关系。然而,交通尾气与胃肠道癌症之间的关系的研究还很缺乏,需要对交通运输工作者进行相关的癌症风险的综合研究。

近日,发表在Sci Rep杂志的一项研究显示,交通运输工作者由于长期接触汽车发动机废气会面临各种患癌风险,比如肺癌,支气管癌以及膀胱癌等。

研究人员使用韩国国民健康保险服务(National Health Insurance Service)数据库分析了暴露于交通空气污染和机动车发动机废气中的道路运输工人(RTW)的癌症风险,包括道路运输工人594,629 人年(person-years),政府雇员有3,268,312人年数,整体工作人口有62,760,615人年。研究人员将3年内首次入院的癌症病史被定义为首次发病病例,并将道路运输工人的癌症发病率,标准发病率(SIR)和95 CI 与其他人口相比较。

结果显示,在肝脏和肝内胆管癌(SIR 1.1595% CI 1.04-1.27)、消化器官癌(SIR 1.2895% CI 1.04-1.57)、气管、支气管和肺癌(SIR 1.2895% CI 1.15-1.43)和膀胱癌(SIR 1.2695% CI 1.03-1.52)方面,RTW的癌症发病率显著高于政府雇员和整体工作人群。当使用3年内固定暴露和动态队列定义时,除了肝癌和肝内胆管癌,其他癌症发病率并没有显著降低。

 

Figure 1

在最初1年固定暴露的队列中,每种癌症风险的SIR和95%置信区间

道路运输工人癌症的年龄标准化发病率和95%置信区间

综上,道路运输工人(RTW)患癌症的风险很高,包括肝癌、肝内胆管癌、其他消化器官癌、气管癌、支气管癌、肺癌和膀胱癌。通过该研究结果可以帮助建立针对道路运输工人(RTW)应对癌症的预防措施。

原始出处

Wanhyung Lee, Mo-Yeol Kang, Jihyun Kim, Sung-Shil Lim & Jin-Ha Yoon. et al.Cancer risk in road transportation workers: a national representative cohort study with 600,000 person-years of follow-up.Scientific Reports 2020

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    2021-01-05 lq0307
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    2021-01-04 12346c4dm64暂无昵称

    职业带来的风险

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2061980, encodeId=cbea20619808c, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Sat Apr 24 23:25:40 CST 2021, time=2021-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413478, encodeId=6a9c14134e887, content=<a href='/topic/show?id=3f225299942' target=_blank style='color:#2F92EE;'>#患癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52999, encryptionId=3f225299942, topicName=患癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b2c2959841, createdName=zzc2212, createdTime=Tue Jan 05 07:25:40 CST 2021, time=2021-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601477, encodeId=46b516014e7f4, content=<a href='/topic/show?id=5baa5299111' target=_blank style='color:#2F92EE;'>#患癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52991, encryptionId=5baa5299111, topicName=患癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=888f18872716, createdName=lq0307, createdTime=Tue Jan 05 07:25:40 CST 2021, time=2021-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913688, encodeId=5f9691368887, content=职业带来的风险, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b2b82397018, createdName=12346c4dm64暂无昵称, createdTime=Mon Jan 04 19:33:59 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913605, encodeId=ed3a913605ad, content=老公一九九八年病世,当时得病孩子才五岁,二年半人就没了,当时就想是职业病,现在与单位要说发不知行不行。, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25645449867, createdName=ms4000001374758153, createdTime=Mon Jan 04 15:06:49 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913603, encodeId=490a91360321, content=两胃癌,一人肝癌,一人喉癌,吓的组是人班长都不干J要求调走。, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25645449867, createdName=ms4000001374758153, createdTime=Mon Jan 04 14:59:21 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913602, encodeId=c5a7913602b1, content=对呀,我老公是做汽车发动机修理的,全组有四人得癌都去世J,我天天想应属公伤,但没人管。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25645449867, createdName=ms4000001374758153, createdTime=Mon Jan 04 14:56:39 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913558, encodeId=8aea9135580b, content=已读,触目惊心, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Mon Jan 04 12:17:36 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913512, encodeId=e4ce913512aa, content=道路运输工人(RTW)患癌症的风险很高,包括肝癌、肝内胆管癌、其他消化器官癌、气管癌、支气管癌、肺癌和膀胱癌。经常在马路上工作的人不容易。, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Jan 04 10:00:34 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913370, encodeId=c3419133e0e2, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=14545449682, createdName=程, createdTime=Sun Jan 03 18:57:24 CST 2021, time=2021-01-03, status=1, ipAttribution=)]
    2021-01-04 ms4000001374758153

    老公一九九八年病世,当时得病孩子才五岁,二年半人就没了,当时就想是职业病,现在与单位要说发不知行不行。

    0

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    2021-01-04 ms4000001374758153

    两胃癌,一人肝癌,一人喉癌,吓的组是人班长都不干J要求调走。

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2061980, encodeId=cbea20619808c, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Sat Apr 24 23:25:40 CST 2021, time=2021-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413478, encodeId=6a9c14134e887, content=<a href='/topic/show?id=3f225299942' target=_blank style='color:#2F92EE;'>#患癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52999, encryptionId=3f225299942, topicName=患癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b2c2959841, createdName=zzc2212, createdTime=Tue Jan 05 07:25:40 CST 2021, time=2021-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601477, encodeId=46b516014e7f4, content=<a href='/topic/show?id=5baa5299111' target=_blank style='color:#2F92EE;'>#患癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52991, encryptionId=5baa5299111, topicName=患癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=888f18872716, createdName=lq0307, createdTime=Tue Jan 05 07:25:40 CST 2021, time=2021-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913688, encodeId=5f9691368887, content=职业带来的风险, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b2b82397018, createdName=12346c4dm64暂无昵称, createdTime=Mon Jan 04 19:33:59 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913605, encodeId=ed3a913605ad, content=老公一九九八年病世,当时得病孩子才五岁,二年半人就没了,当时就想是职业病,现在与单位要说发不知行不行。, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25645449867, createdName=ms4000001374758153, createdTime=Mon Jan 04 15:06:49 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913603, encodeId=490a91360321, content=两胃癌,一人肝癌,一人喉癌,吓的组是人班长都不干J要求调走。, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25645449867, createdName=ms4000001374758153, createdTime=Mon Jan 04 14:59:21 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913602, encodeId=c5a7913602b1, content=对呀,我老公是做汽车发动机修理的,全组有四人得癌都去世J,我天天想应属公伤,但没人管。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25645449867, createdName=ms4000001374758153, createdTime=Mon Jan 04 14:56:39 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913558, encodeId=8aea9135580b, content=已读,触目惊心, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Mon Jan 04 12:17:36 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913512, encodeId=e4ce913512aa, content=道路运输工人(RTW)患癌症的风险很高,包括肝癌、肝内胆管癌、其他消化器官癌、气管癌、支气管癌、肺癌和膀胱癌。经常在马路上工作的人不容易。, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Jan 04 10:00:34 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913370, encodeId=c3419133e0e2, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=14545449682, createdName=程, createdTime=Sun Jan 03 18:57:24 CST 2021, time=2021-01-03, status=1, ipAttribution=)]
    2021-01-04 ms4000001374758153

    对呀,我老公是做汽车发动机修理的,全组有四人得癌都去世J,我天天想应属公伤,但没人管。

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2061980, encodeId=cbea20619808c, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Sat Apr 24 23:25:40 CST 2021, time=2021-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413478, encodeId=6a9c14134e887, content=<a href='/topic/show?id=3f225299942' target=_blank style='color:#2F92EE;'>#患癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52999, encryptionId=3f225299942, topicName=患癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b2c2959841, createdName=zzc2212, createdTime=Tue Jan 05 07:25:40 CST 2021, time=2021-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601477, encodeId=46b516014e7f4, content=<a href='/topic/show?id=5baa5299111' target=_blank style='color:#2F92EE;'>#患癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52991, encryptionId=5baa5299111, topicName=患癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=888f18872716, createdName=lq0307, createdTime=Tue Jan 05 07:25:40 CST 2021, time=2021-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913688, encodeId=5f9691368887, content=职业带来的风险, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b2b82397018, createdName=12346c4dm64暂无昵称, createdTime=Mon Jan 04 19:33:59 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913605, encodeId=ed3a913605ad, content=老公一九九八年病世,当时得病孩子才五岁,二年半人就没了,当时就想是职业病,现在与单位要说发不知行不行。, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25645449867, createdName=ms4000001374758153, createdTime=Mon Jan 04 15:06:49 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913603, encodeId=490a91360321, content=两胃癌,一人肝癌,一人喉癌,吓的组是人班长都不干J要求调走。, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25645449867, createdName=ms4000001374758153, createdTime=Mon Jan 04 14:59:21 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913602, encodeId=c5a7913602b1, content=对呀,我老公是做汽车发动机修理的,全组有四人得癌都去世J,我天天想应属公伤,但没人管。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25645449867, createdName=ms4000001374758153, createdTime=Mon Jan 04 14:56:39 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913558, encodeId=8aea9135580b, content=已读,触目惊心, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Mon Jan 04 12:17:36 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913512, encodeId=e4ce913512aa, content=道路运输工人(RTW)患癌症的风险很高,包括肝癌、肝内胆管癌、其他消化器官癌、气管癌、支气管癌、肺癌和膀胱癌。经常在马路上工作的人不容易。, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Jan 04 10:00:34 CST 2021, time=2021-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=913370, encodeId=c3419133e0e2, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=14545449682, createdName=程, createdTime=Sun Jan 03 18:57:24 CST 2021, time=2021-01-03, status=1, ipAttribution=)]
    2021-01-04 ms5000000518166734

    已读,触目惊心

    0

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    2021-01-04 Jessica

    道路运输工人(RTW)患癌症的风险很高,包括肝癌、肝内胆管癌、其他消化器官癌、气管癌、支气管癌、肺癌和膀胱癌。经常在马路上工作的人不容易。

    0

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    2021-01-03

    0