《围手术期非小细胞肺癌国际专家诊疗共识》即将重磅发布

2022-08-05 AME科研时间 AME科研时间 发表于上海

一起来围观~

肺癌是全球癌症相关死亡的最常见原因,非小细胞肺癌(non-small-cell lung cancerNSCLC)在肺癌中占比约85%。外科根治性手术切除是期、期及部分ⅢANSCLC患者的主要治疗方式。但超过50%仅接受手术的患者会在5年内出现复发或转移,这成为了临床上肺癌围手术期管理的一大挑战。

化疗是目前围手术期肺癌新辅助及辅助治疗应用最主要的治疗手段,但围手术期化疗带来的生存获益相对有限,5年生存率提高约5%

近年来随着免疫和靶向治疗从晚期肺癌前移到早期阶段,围手术期肺癌治疗的研究开始披荆斩棘,突破重围。ADAURA研究令驱动基因阳性的NSCLC患者的辅助靶向治疗受到了临床上广泛认可;CTONG-1103研究则提示了新辅助靶向治疗的临床应用价值;IMpower010研究开启了早期NSCLC辅助免疫治疗的新时代;CheckMate-816研究亦证实新辅助免疫治疗为早期NSCLC患者带来了显著临床获益……总体而言,围手术期肺癌领域的研究进展为NSCLC患者带来了可观的获益。

围手术期NSCLC的治疗新格局正在逐渐形成,随着研究进展日新月异,针对围手术期NSCLC的诊疗目前仍然缺乏一部能够覆盖围手术期全程管理的专家共识。在此背景下,《围手术期非小细胞肺癌国际专家诊疗共识》(以下简称《共识》)应运而生!

厚积薄发,终露锋芒。该《共识》由中国医学科学院肿瘤医院高树庚教授和王洁教授牵头,汇聚海内外四十余位专家学者的真知灼见,以围手术期NSCLC循证医学为基础,深耕细作,历经淬炼沉淀,已顺利完成相关编撰工作,终稿已于Translational Lung Cancer Research(《肺癌转化研究》,简称TLCR)杂志7月刊正式刊出。

该《共识》的制定,对于中国肺癌治疗领域的发展具有举足轻重的意义。《共识》围绕着病理诊断和生物标志物检测、NSCLC患者的新辅助治疗、驱动基因突变阳性NSCLC患者的辅助靶向治疗、NSCLC患者的辅助免疫治疗和围手术期NSCLC患者管理五大临床关键议题,为临床医生提供更具实操性的指导意见,这将进一步推动NSCLC围手术期的规范化诊疗,为围手术期NSCLC患者的早期规范化诊断、早期规范化治疗及随访管理提供强有力的证据和支持,从而惠及围手术期NSCLC患者,在提高患者生活质量的同时,延长患者的生存。

86日上午9时,《围手术期非小细胞肺癌国际专家诊疗共识》将以线上形式重磅发布(扫描下方二维码观看)。《共识》制定牵头人高树庚教授、王洁教授以及参与共识制定的二十余位国内肺癌领域知名专家学者将在云端共启《共识》发布仪式,共同见证这一重磅时刻。

扫描上方二维码观看《共识》发布

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