Hypertension:这两种几亿中国人都有的病,合起来更危险!

2018-04-29 佚名 康健新视野

近日,中国医学科学院阜外医院李建军教授团队,在美国心脏学会旗下期刊《Hypertension》发表了一项重要的临床研究数据:冠状动脉造影新诊断的稳定性冠心病患者中,单纯的糖尿病前期,并不会导致心血管事件风险升高,而糖尿病前期同时合并高血压时,或者糖尿病同时合并高血压时,则会导致严重冠脉病变事件风险显著升高。

血管疾病(CVD)仍然是全世界最常见的慢性病之一,发病率和死亡率较高。而关于心血管风险,目前频繁讨论的问题是,糖尿病前期(pre-DM)是否是心血管疾病风险的独立危险因素,糖尿病前期是否需要及时干预,以预防 CVD 风险。

近日,中国医学科学院阜外医院李建军教授团队,在美国心脏学会旗下期刊《Hypertension》发表了一项重要的临床研究数据:冠状动脉造影新诊断的稳定性冠心病患者中,单纯的糖尿病前期,并不会导致心血管事件风险升高,而糖尿病前期同时合并高血压时,或者糖尿病同时合并高血压时,则会导致严重冠脉病变事件风险显着升高。


该研究的主要作者李建军教授(图片来源:中国医学科学院阜外医院官网)

李建军教授团队筛查分析了 4193 例通过血管造影确诊为稳定型冠心病患者资料,进一步将这些患者按照合并糖尿病状态细分成 3 组:血糖正常组(NGR)、糖尿病前期(Pre-DM)、和糖尿病组,对比分析了这 3 组患者冠状动脉病变严重程度,并定期随访心血管复合终点事件的发生风险。分析中,将高血压因素纳入了分层因素。

该研究结果的核心数据如下:

平均随访 11 338 病例年后, 观察到了 434 (10.35%) 例心血管事件发生;

Pre-DM 组相比血糖正常组,无论冠心病严重程度,还是复合心血管终点事件风险,均无显无显着性差异 (P>0.05);

按高血压状态进行分层分析发现,相比血糖和血压都正常的患者,无论糖尿病前期合并高血压者还是糖尿病合并高血压者,心血管疾病的风险均显着升高.

原始出处:

Hui-Hui Liu, Ye-Xuan Cao, Sha Li, et al. Impacts of Prediabetes Mellitus Alone or Plus Hypertension on the Coronary Severity and Cardiovascular Outcomes. Hypertension. 2018;HYPERTENSIONAHA.118.11063, originally published April 18, 2018.

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    2018-10-26 feather89
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    2018-05-02 半夏微凉

    学习了谢谢分享

    0

  4. 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attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue May 01 00:27:24 CST 2018, time=2018-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=310822, encodeId=9914310822a9, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue May 01 00:27:16 CST 2018, time=2018-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=310821, encodeId=781631082109, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue May 01 00:27:05 CST 2018, time=2018-05-01, status=1, ipAttribution=)]
    2018-05-01 smartxiuxiu

    0

  5. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue May 01 00:27:05 CST 2018, time=2018-05-01, status=1, ipAttribution=)]
    2018-05-01 Ramsey

    慢病的管理越来越重要了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1727265, encodeId=9bd41e2726568, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Oct 26 05:42:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2038893, encodeId=96e5203889325, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue May 01 00:27:05 CST 2018, time=2018-05-01, status=1, ipAttribution=)]
    2018-05-01 Y—xianghai

    学习了长知识

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue May 01 00:27:05 CST 2018, time=2018-05-01, status=1, ipAttribution=)]
    2018-05-01 Y—xianghai

    学习了长知识

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue May 01 00:27:05 CST 2018, time=2018-05-01, status=1, ipAttribution=)]
    2018-05-01 Y—xianghai

    学习了新知识

    0

  9. 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    2018-05-01 Y—xianghai

    学习了长知识

    0

  10. 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    2018-05-01 Y—xianghai

    学习了长知识

    0

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