JAHA:心脏手术后的无症状脑梗死

2019-04-25 xiangting MedSci原创

SBIs是心脏手术后很常见的并发症,特别是那些涉及主动脉瓣的手术。

无症状脑梗死(SBI)越来越多地被认为是心脏手术的重要并发症,也是脑损伤研究的潜在替代指标。亚临床脑损伤的程度尚未被明确定义。

研究人员利用心脏手术后的SBIs和局灶性神经功能缺损研究进行了一项系统评价和荟萃分析。最终分析包括42项研究,49个独立的治疗组,共2632名患者。经导管主动脉瓣植入术后SBIs的患病率为0.71(95%CI 0.64-0.77);主动脉瓣置换术后为0.44(95%CI 0.31-0.57);心胸外科手术组为0.39(95%CI 0.28-0.49);冠脉旁路移植术为0.25(95%CI 0.15-0.35);经皮冠脉介入治疗为0.14(95%CI 0.10-0.19);非体外循环冠脉搭桥为0.14(0.00-0.58)。主动脉瓣置换术中局灶性神经功能缺损与SBI的风险比为0.22(95%CI 0.15-0.32);非体外循环冠脉旁路为0.21(95%CI 0.02-2.04);心胸外科手术为0.15(95%CI 0.07-0.33);冠脉搭桥术为0.10(95%CI 0.05-0.18);经导管主动脉瓣植入为0.10(95%CI 0.07-0.14);经皮冠脉介入治疗为0.06(95%CI 0.03-0.14)。与主动脉瓣置换组(2.16±1.62,P=0.03)和经皮冠脉介入治疗组(1.88±1.02,P=0.03)相比,经导管主动脉瓣置入组每位患者的SBIs平均数显著升高(4.58±2.09)。

SBIs是心脏手术后很常见的并发症,特别是那些涉及主动脉瓣的手术。与卒中相比,SBIs很常见,这强调了在心脏介入研究中记录这种替代指标的重要性。这项研究建议进一步工作以标准化报告,以便于使用SBIs作为常规结局测量。

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    2019-04-27 仁心济世
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    2019-04-27 karmond
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    2019-04-26 深海的鱼

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