PCI与尿激酶联合应用成功治疗左前降支血栓性病变(图)

2015-12-02 网络 MedSci原创

PCI与尿激酶联合应用成功治疗左前降支血栓性病变

PCI与尿激酶联合应用成功治疗左前降支血栓性病变

PCI与尿激酶联合应用成功治疗左前降支血栓性病变

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    2015-12-04 redcrab
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J Cell Sci:蛋白激酶通过尿激酶促进前列腺癌侵袭转移

蛋白激酶D3(PKD3)虽然已被证明有助于前列腺癌细胞的生长和生存,但其在前列腺癌细胞运动中的作用仍不清楚。 近日,一项刊登在J Cell Sci杂志上的研究表明PKD2和PKD3激活核因子-κB(NF-κB)信号和促进尿激酶型纤溶酶原激活因子(uPA)的表达/激活,而后两者对前列腺癌细胞的侵袭是至关重要的。 沉默内源性PKD2或/和 PKD3的表达能显著降低前列腺癌的细胞迁移和侵袭,同时uP