中国将肿瘤电场治疗纳入标准方案 国际前沿创新疗法造福胶质母细胞瘤患者

2020-07-05 中国新闻网 中国新闻网

胶质母细胞瘤是最常见的原发性恶性中枢神经系统肿瘤,被认为是神经外科治疗中最棘手的难治性肿瘤之一。手术加上放疗和化疗一直是该疾病的传统治疗方案。

中国将肿瘤电场治疗纳入标准方案国际前沿创新疗法造福胶质母细胞瘤患者

秦智勇表示,胶质母细胞瘤患者临床预后极差。“手术+放化疗+肿瘤电场治疗”将成新的标准治疗方案。 陈静 摄

中新网上海6月30日电 (记者 陈静)胶质母细胞瘤是最常见的原发性恶性中枢神经系统肿瘤,被认为是神经外科治疗中最棘手的难治性肿瘤之一。手术加上放疗和化疗一直是该疾病的传统治疗方案。

记者30日获悉,上海将国际前沿的创新疗法——电场治疗纳入胶质母细胞瘤的治疗方案,造福众多胶质母细胞瘤患者。今后,“手术+放化疗+肿瘤电场治疗”将成新的标准治疗方案”。

张先生30日开始接受肿瘤电场治疗。 陈静 摄

张先生30日开始接受肿瘤电场治疗。 陈静 摄

当日,由中国初级卫生保健基金会发起、针对胶质母细胞瘤患者的慈善援助项目在上海启动,以切实提高创新治疗手段的可及性,帮助更多胶质母细胞瘤患者减轻经济负担,更早获得及时有效的标准治疗。

中国初级卫生保健基金会副理事长胡宁宁表示,希望援助项目能帮助更多胶质母细胞瘤患者第一时间获得优质的治疗方案,最大程度降低患者和家庭的经济负担,增强患者与疾病抗争的信心,助力实现“健康中国2030”总体癌症5年生存率提高15%的目标。据悉,符合条件的低保和低收入胶质母细胞瘤患者均可申请。

复旦大学附属华山医院神经外科秦智勇教授当日接受记者采访时介绍,肿瘤电场治疗是一种便携、无创的全新肿瘤治疗方案,其作用机制是通过低强度、中频交流电场,作用于增殖肿瘤细胞的微管蛋白,可通过干扰肿瘤细胞有丝分裂,抑制肿瘤增长并使受电场影响的癌细胞死亡。

胶质母细胞瘤恶性程度高、生长快、病程短、术后易复发且高致残,最具侵袭性。秦智勇表示,胶质母细胞瘤患者临床预后极差,中位生存期仅为15个月,复发率接近100%,五年生存率约5%。

秦智勇坦言:“多年来,胶质母细胞瘤的治疗方案更新十分缓慢,在其他肿瘤治疗中大热的靶向治疗和免疫治疗在胶质母细胞瘤中仍处在不断探索阶段。只有创新疗法肿瘤电场治疗经国际大规模临床试验证实了治疗的有效性和安全性,并被纳入国际权威指南。”

这位专家介绍,在中国,二十年前,胶质母细胞瘤是不治之症,患者预期寿命只有6-8个月;如今,以华山医院为例,胶质母细胞瘤患者的预期中位生存时间可以达到16-18个月。肿瘤电场治疗成为15年来中国胶质母细胞瘤治疗的重大突破,具有划时代的重要意义。他表示,不久前,肿瘤电场治疗在中国获批上市,未来将进入临床应用,我们期待患者可以活得更长、活得更好。”

48岁的张先生是一名胶质母细胞瘤患者,曾在3月份接受手术切除,并在随后两个月接受放化疗治疗。当日,他开始接受肿瘤电场治疗。张先生对记者表示:“希望这是我全新生命旅程的开始!”(完)

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    2020-07-06 kcb074
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    2020-07-05 金黎明

    如何申请?

    0

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J Cell Physiol:弥漫性低级胶质瘤的肿瘤微环境中的免疫相关基因和免疫细胞浸润的研究报告

肿瘤微环境与肿瘤的发生、进展和预后高度相关。本研究旨在探究低级胶质瘤(LGG)肿瘤微环境中免疫相关基因(IRG)的表达和免疫浸润模式。