Lancet Gastroen Hepatol:2016年度乙型肝炎病毒感染的全球流行、治疗与预防

2018-03-27 zhangfan MedSci原创

研究人员对2016年度全球HBV感染情况进行考察,该研究为全面消除HBV感染威胁提供了重要的数据支持

第69届世界卫生大会通过的全球卫生战略计划到2030年全面消除病毒性肝炎。尽管目前尚无完全消除HBV病毒的方法,但现行的控制病毒复制和预防治疗方法可以最大限度地减少母婴传播。近日研究人员就2016年度国家、地区和全球一般人群和5岁幼儿中HBsAg的流行率,以及预防诊断和治疗情况进行考察。

研究人员利用Delphi程序对PubMed以及Embase数据库数据进行考察,采用动态模型来考察乙肝传播和进展,估计2016年度国家和地区两级的乙肝表面抗原流行率、预防和治疗对疾病负担的影响。

120个国家参与研究,2016年全球HBsAg阳性率约为3.9%,总计291992000例感染,其中仅2900万感染者得到确诊(10%),而仅有480万人得到抗病毒治疗。5岁幼儿感染者约180万。87%的婴儿在出生后第一年就接种了三次乙肝疫苗,46%的婴儿出生时及时接种了疫苗,13%的婴儿接受了乙肝免疫球蛋白和完整的疫苗接种方案,但仅有不到1%的高病毒当量母亲接受了母婴传播阻断。

研究人员对2016年度全球HBV感染情况进行考察,该研究为全面消除HBV感染威胁提供了重要的数据支持。

原始出处:

The Polaris Observatory Collaborators. Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study.Lancet Gastroen Hepatol. 26 March 2018.

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    2019-02-06 许安
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topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Tue Mar 12 05:21:00 CST 2019, time=2019-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1825655, encodeId=f7421825655a2, content=<a href='/topic/show?id=1a942339426' target=_blank style='color:#2F92EE;'>#乙型肝炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23394, encryptionId=1a942339426, topicName=乙型肝炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea6321, createdName=okhuali, createdTime=Tue Sep 11 10:21:00 CST 2018, time=2018-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300790, encodeId=6d2f300e909f, content=不错耶.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Mar 29 07:25:37 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300723, encodeId=b5f2300e2319, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Thu Mar 29 06:49:12 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351545, encodeId=0fb713515451d, content=<a href='/topic/show?id=74672339e92' target=_blank style='color:#2F92EE;'>#乙型肝炎病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23397, encryptionId=74672339e92, topicName=乙型肝炎病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Mar 29 04:21:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1427057, encodeId=acfc142e0575f, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Thu Mar 29 04:21:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300329, encodeId=ab173003291e, content=2016年度乙型肝炎病毒感染的全球流行.治疗与预防, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Tue Mar 27 23:27:17 CST 2018, time=2018-03-27, status=1, ipAttribution=)]
    2019-03-12 howi
  5. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Mar 29 07:25:37 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300723, encodeId=b5f2300e2319, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Thu Mar 29 06:49:12 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351545, encodeId=0fb713515451d, content=<a href='/topic/show?id=74672339e92' target=_blank style='color:#2F92EE;'>#乙型肝炎病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23397, encryptionId=74672339e92, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Tue Mar 27 23:27:17 CST 2018, time=2018-03-27, status=1, ipAttribution=)]
  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Mar 29 07:25:37 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300723, encodeId=b5f2300e2319, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Thu Mar 29 06:49:12 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351545, encodeId=0fb713515451d, content=<a href='/topic/show?id=74672339e92' target=_blank style='color:#2F92EE;'>#乙型肝炎病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23397, encryptionId=74672339e92, topicName=乙型肝炎病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Mar 29 04:21:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1427057, encodeId=acfc142e0575f, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Thu Mar 29 04:21:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300329, encodeId=ab173003291e, content=2016年度乙型肝炎病毒感染的全球流行.治疗与预防, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Tue Mar 27 23:27:17 CST 2018, time=2018-03-27, status=1, ipAttribution=)]
    2018-03-29 owlhealth

    不错耶.学习了

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Mar 29 07:25:37 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300723, encodeId=b5f2300e2319, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Thu Mar 29 06:49:12 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351545, encodeId=0fb713515451d, content=<a href='/topic/show?id=74672339e92' target=_blank style='color:#2F92EE;'>#乙型肝炎病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23397, encryptionId=74672339e92, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Tue Mar 27 23:27:17 CST 2018, time=2018-03-27, status=1, ipAttribution=)]
    2018-03-29 yfjms

    学习

    0

  8. 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    2018-03-29 gwc384
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    2018-03-27 ann y

    2016年度乙型肝炎病毒感染的全球流行.治疗与预防

    0

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