BMJ子刊:1990-2019年中国1型和2型糖尿病的长期发病率趋势和人口老龄化对死亡率的影响

2021-11-05 MedSci原创 MedSci原创

根据中国最新的全国调查,糖尿病患病率从1980年的0.67%上升到2017年的11.2%(按照世界卫生组织糖尿病的诊断标准)。

根据中国最新的全国调查,糖尿病患病率从1980年的0.67%上升到2017年的11.2%(按照世界卫生组织糖尿病的诊断标准)。糖尿病的患病率对于指导分配糖尿病管理资源非常重要,尽管有两项研究使用全球疾病负担(GBD)数据库分析了中国糖尿病的发病率趋势,但他们的结果将1型糖尿病(T1DM)和2型糖尿病(T2DM)合并为一个类别进行分析。然而,T1DM与T2DM的流行病学特征存在显著差异。

糖尿病和人口老龄化已成为全球关注的公共卫生问题。中国1型糖尿病(T1DM)和2型糖尿病(T2DM)的长期发病率趋势及人口老龄化对死亡率的影响尚不清楚。

基于此,本研究从全球疾病负担研究(GBD) 2019年数据库中提取了1990年至2019年T1DM和T2DM的发病率和死亡率。采用联合回归和年龄期队列模型分别计算年平均百分比变化和相对风险(RR)。采用分解方法将总死亡的变化归因于1990年至2019年的人口增长、人口老龄化和死亡率变化。

1990年至2019年与人口老龄化、人口增长和死亡率变化相关的T1DM相关和T2DM相关死亡人数的变化

研究结果显示,从1990年到2019年,T1DM年龄标准化发病率(ASIR)男性上升2.01%,女性上升1.70%,T1DM年龄标准化死亡率(ASMR)男性下降1.96%,女性下降4.02%。T2DM ASIR男性增加0.81%,女性增加0.37%,T2DM ASMR男性增加1.06%,女性减少0.24%。与1990年相比,2019年因人口老龄化导致的死亡比例男性为18.85%(T1DM)至148.21%(T2DM),女性为29.80%(T1DM)至118.82%(T2DM)。

总而言之,国的T1DM和T2DM发病率持续上升,尤其是年轻人。男性T1DM相关死亡率下降,而T2DM相关死亡率上升。人口老龄化可能与1990年至2019年死亡人数的重大变化有关。为了解决因人口老龄化导致的2型糖尿病相关死亡增加的问题,决策者应促进与老龄化相关的健康研究,并实施经验证的、具有成本效益的2型糖尿病干预措施。

参考文献:Li YGuo CCao YSecular incidence trends and effect of population aging on mortality due to type 1 and type 2 diabetes mellitus in China from 1990 to 2019: findings from the Global Burden of Disease Study 2019.

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    2022-05-16 gaoxiaoe
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    2021-11-05 419040982

    这个应该好好的干预!

    0

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