2006-2016 诺贝尔生理学或医学奖获奖名单

2016-10-03 MedSci MedSci原创

诺贝尔生理学或医学奖在很长时间内已经成为公众中认识度最高的生物医学类奖项,一旦获此殊荣,即会成为举世瞩目的科学家,受到各国人民的膜拜。去年屠呦呦凭借青蒿素成为第一位获得诺贝尔科学奖项的中国本土科学家后,更加贴近了中国与诺贝尔奖的距离。下面,我们来一起重温一下近年内的诺贝尔生理学与医学奖得主的风采~2006年,安德鲁·法尔(Andrew Zachary Fire)和克雷格·梅洛(Craig Ca

据诺贝尔奖官网的最新消息,瑞典斯德哥尔摩当地时间10月3日中午11时30分,2016年诺贝尔生理学或医学奖在瑞典卡罗林斯卡医学院颁布揭晓,该奖项颁发给日本分子细胞生物学家Yoshinori Ohsumi(大隅良典),以表彰其在基因自噬方面的卓越贡献。



Yoshinori Ohsumi(大隅良典)

下面,我们来一起重温一下近十年内的诺贝尔生理学或医学奖获奖科学家的风采~

2006年,安德鲁·法尔(Andrew Zachary Fire)和克雷格·梅洛(Craig Cameron Mello)


2006年,美国人安德鲁·法尔和克雷格·梅洛凭借 "RNA干扰机制--双链RNA沉默基因" 的发现脱颖而出,成为该年度诺贝尔生理学或医学奖得主。虽奖项名目既涉及生理学,也涉及医学,但针对这两位获奖者及其成果,欧美媒体无不把今年这一奖项称为诺贝尔医学奖。法尔和梅洛以遗传学为切入点,选择针对核糖核酸(RNA)的干扰机制作为研究课题。该机制已被广泛用作研究基因功能的一种手段,并有望在未来帮助科学家开发出治疗疾病的新疗法。

2007年,奥利弗·史密斯(Oliver Smithies)和马丁·埃文斯(Martin J. Evans)、马里奥·卡佩基(Mario R. Capecchi)
2007年,来自英美两国的奥利弗o史密斯(Oliver Smithies)和马丁o埃文斯(Martin J. Evans)、马里奥o卡佩基(Mario R. Capecchi)三位科学家,获得该年诺贝尔生理学或医学奖。诺贝尔奖评审委员会发布的公报说,三位科学家"在涉及胚胎干细胞和哺乳动物DNA重组方面有着一系列突破性发现",使深入研究单个基因在动物体内的功能并提供相关药物试验的动物模型成为可能,为"基因靶向"技术的发展奠定了基础。

2008年,弗朗索瓦丝·巴尔-西诺西(Fran?oise Barré-Sinoussi)和吕克·蒙塔尼(Luc Montagnier)、哈拉尔德·楚尔·豪森(Harald zur Hausen)


2008年,三名欧洲科学家因为发现两种引发人类致命疾病的病毒而荣获2008年诺贝尔生理学或医学奖。两名法国科学家弗朗索瓦丝·巴尔-西诺西和吕克·蒙塔尼上世纪80年代发现人类免疫缺陷病毒,使医学界找到了确诊艾滋病病毒感染的办法,延缓了这种病毒的传播。德国科学家哈拉尔德·楚尔·豪森在上世纪70年代开始的研究中发现导致宫颈癌的HPV(人乳头状瘤病毒),为宫颈癌疫苗今天的诞生奠定了基础。

2009年,卡罗尔·格雷德(CarolW.Greider)、伊丽莎白·布莱克本(ElizabethH.Blackburn)、杰克·绍斯塔克(JackW.Szostak)


2009年,美国加利福尼亚旧金山大学的伊丽莎白·布莱克本(ElizabethH.Blackburn)、美国巴尔的摩约翰·霍普金斯医 学院的卡罗尔·格雷德(CarolW.Greider)、美国哈佛医学院的杰克·绍斯塔克(JackW.Szostak)因发现端粒和端粒酶保护染色体的机理而获此殊荣。该研究提高了人们对于细胞的理解的深度,对癌症和衰老研究具有重要的意义,有助于未来新治疗方法的发展。

2010年,罗伯特·爱德华(Robert G. Edwards)


2010年,英国生理学家,被称为"试管婴儿之父"的罗伯特·爱德华兹因为在"在试管受精技术方面的发展"获得2010年诺贝尔生理学或医学奖。爱德华兹创立的体外受精技术解决了一个重要的医学难题,即通过体外受精治疗多种不育症。他的贡献使治疗不育症成为可能,包括全球超过10%的夫妇在内的人类因此获益匪浅。

2011年,拉尔夫·斯坦曼因(Ralph M. Steinman)和朱尔斯·霍夫曼(Jules A. Hoffmann)、布鲁斯·博伊特勒(Bruce A. Beutler)


2011年,加拿大科学家拉尔夫·斯坦曼、法国科学家朱尔斯·霍夫曼、美国科学家布鲁斯·博伊特勒因在免疫学领域取得杰出成就而获得2011年诺贝尔生理学或医学奖。其中一半的奖金归于拉尔夫·斯坦曼,获奖理由是"发现树枝状细胞及其在获得性免疫中的作用" ;另一半奖金归于朱尔斯·霍夫曼和布鲁斯·博伊特勒,获奖理由是"先天免疫激活方面的发现"。这三位诺奖得主发现了免疫系统激活的关键原理,从而彻底革新了我们对免疫系统的认识。

2012年,约翰o格登(John Gurdon) 、山中伸弥(Shinya Yamanaka)


2012年,英国科学家约翰o格登(John Gurdon) 与日本科学家山中伸弥(Shinya Yamanaka)因在细胞核重新编程研究领域的杰出贡献,获得2012年诺贝尔生理学或医学奖。诺贝尔奖认为,这两位科学家发现了:成熟、分化的细胞可以被重新编程,变成未成熟的细胞,能够发育成机体内所有种类的组织。他们的发现革新了我们对于细胞和有机体如何发育的理解。

2013年,詹姆斯·罗斯曼(James E. Rothman),兰迪·谢克曼(Randy W. Schekman)和托马斯·聚德霍夫(Thomas C. Südhof)


2013年,耶鲁大学细胞生物学系系主任、生物医学教授詹姆斯·罗斯曼(James E. Rothman),加州大学伯克利分校的细胞生物学家兰迪·谢克曼(Randy W. Schekman)和德国生物化学家托马斯·聚德霍夫(Thomas C. Südhof),因"发现细胞内的主要运输系统--囊泡运输的调节机制"获得2013年诺贝尔生理学或医学奖。诺贝尔奖评选委员会说,三位获奖者的研究成果揭示了细胞如何在准确的时间将其内部物质传输至准确的位置,揭示出细胞生理学的一个基本过程。

2014年,爱德华·莫泽(Edvard I. Moser))和梅-布里特·莫泽(May-Britt Moser)、约翰·奥基夫(John O'Keefe)


2014年,来自挪威的科学家爱德华·莫泽(Edvard I. Moser))和梅-布里特·莫泽(May-Britt Moser),以及英国伦敦大学学院教授约翰·奥基夫(John O'Keefe)夫妇共三位科学家,因发现组成大脑定位系统(GPS)的特殊细胞的研究成果获得该年诺贝尔生理学或医学奖。解决了哲学家和科学家几个世纪之久的问题--人类大脑究竟是如何构建一个所处空间的地图,以及在一个复杂的环境中人类大脑如何导航并寻找路径。

2015年,威廉·C·坎贝尔(William C. Campbell)、屠呦呦和大村智(Satoshi ōmura)


2015年诺贝尔生理学或医学奖揭晓,我国科学家屠呦呦获奖!获奖理由是"有关疟疾新疗法的发现"。另外两名获奖科学家为爱尔兰的William C. Campbell和日本的Satoshi ōmura,获奖理由是"有关蛔虫寄生虫感染新疗法的发现"。这两项发现为人类提供了强有力的新武器,从而使得人类能够与这些每年感染亿万人的疾病作斗争。其为人类改善健康、减轻病痛所带来的功德不可估量。

2016年,Yoshinori Ohsumi(大隅良典)


Yoshinori Ohsumi生于1945年,1974年在东京大学获得博士学位!然后进入Rockefeller 大学三年,1988年返回东京大学建立自己的研究室。2009年至今任东京技术研究所教授。

Yoshinori Ohsumi(大隅良典)教授克隆了第一个酵母自噬基因Atg1和LC3,发挥了决定性作用!大隅良典教授是细胞自噬研究的先驱,曾获得京都奖、盖尔德纳国际奖及日本人第2座威利奖(2015年加拿大盖尔德纳奖揭晓)。其专长生物学,特别是分子生物学领域。最知名的成就,是阐明细胞自噬的分子机制和生理功能。由于相关论文被大量引用,因此名列2014年度汤森路透引文桂冠奖。

#2016诺贝尔医学奖与生理学奖#  自噬转化医学与疾病研讨会,详情点击:http://www.bioon.com/z/2016autophagy/

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    2016-10-05 1dee1b88m43(暂无匿称)

    中国加油!

    0

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GetPortalCommentsPageByObjectIdResponse(id=140171, encodeId=c0111401e181, content=学习啦,,好伟大的, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Tue Oct 04 23:37:03 CST 2016, time=2016-10-04, status=1, ipAttribution=)]
    2016-10-05 刘煜

    阅读了谢谢。

    0

  10. 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    2016-10-04 医路开来

    学习啦,,好伟大的

    0

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