Diabetes Care:二甲双胍减少糖尿病患者胃癌风险 ,可能与降低幽门螺杆菌感染有关

2018-02-14 MedSci MedSci原创

有研究表明糖尿病患者的胃癌患病风险增加,也有研究发现降糖药二甲双胍有助于预防胃癌。幽门螺杆菌是导致胃癌的重要危险因素,有研究者想探讨二甲双胍这种降糖药是否能够降低2型糖尿病患者的幽门螺杆菌感染率,从而降低幽门螺旋杆菌导致胃癌的风险。研究者对中国台湾地区1999-2005年间的国民健康保险库进行数据收集及分析,选择患有糖尿病的研究对象,根据是否服用二甲双胍给糖尿病患者进行分组和配对,配对时考虑到年龄

有研究表明糖尿病患者的胃癌患病风险增加,也有研究发现降糖药二甲双胍有助于预防胃癌。幽门螺杆菌是导致胃癌的重要危险因素,有研究者想探讨二甲双胍这种降糖药是否能够降低2型糖尿病患者的幽门螺杆菌感染率,从而降低幽门螺旋杆菌导致胃癌的风险。研究者对中国台湾地区1999-2005年间的国民健康保险库进行数据收集及分析,选择患有糖尿病的研究对象,根据是否服用二甲双胍给糖尿病患者进行分组和配对,配对时考虑到年龄、性别、职业、生活区域、高血压、血脂异常、肥胖、肾病、眼病、中风、缺血性心脏病、外周动脉疾病、慢性阻塞性肺病、吸烟、酒精依赖、心力衰竭、牙龈和牙周炎、肺炎、骨质疏松症、肺结核感染、胰腺疾病、食道疾病、胃和十二指肠疾病、EB病毒感染、乙型肝炎病毒感染、丙型肝炎病毒感染等因素,同时也考虑了使用其他药物(胰岛素、磺脲类、格列奈类、阿卡波糖、罗格列酮、吡格列酮、ACE抑制剂/血管紧张素受体阻滞剂、钙通道阻滞剂、他汀类、纤维化剂和阿司匹林)的因素。研究总共纳入16060名曾经使用过二甲双胍的糖尿病患者,以及16060名新诊断的从未接受过治疗的糖尿病患者。入选对象年龄在25~75岁之间,对于1型糖尿病患者

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    2020-07-21 lovetcm

    #二甲双胍#神药💊再现!

    0

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encodeId=dc1b288968ff, content=谢谢.祝梅斯医学越来越好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Feb 18 18:31:38 CST 2018, time=2018-02-18, status=1, ipAttribution=)]
    2018-11-30 kcb069
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    2019-01-01 sjq027
  7. 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encodeId=dc1b288968ff, content=谢谢.祝梅斯医学越来越好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Feb 18 18:31:38 CST 2018, time=2018-02-18, status=1, ipAttribution=)]
    2018-02-26 惠映实验室

    学习.谢谢分享.

    0

  8. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289865, encodeId=87ae289865bd, content=****减少糖尿病患者胃癌风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Thu Feb 22 07:25:09 CST 2018, time=2018-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289580, encodeId=b56c28958013, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Wed Feb 21 06:12:30 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288968, encodeId=dc1b288968ff, content=谢谢.祝梅斯医学越来越好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Feb 18 18:31:38 CST 2018, time=2018-02-18, status=1, ipAttribution=)]
    2018-02-22 jyzxjiangqin

    ****减少糖尿病患者胃癌风险.

    0

  9. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289865, encodeId=87ae289865bd, content=****减少糖尿病患者胃癌风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Thu Feb 22 07:25:09 CST 2018, time=2018-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289580, encodeId=b56c28958013, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Wed Feb 21 06:12:30 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288968, encodeId=dc1b288968ff, content=谢谢.祝梅斯医学越来越好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Feb 18 18:31:38 CST 2018, time=2018-02-18, status=1, ipAttribution=)]
    2018-02-21 121832a9m88暂无昵称

    学习了

    0

  10. 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href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Tue Jan 01 05:43:00 CST 2019, time=2019-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=291155, encodeId=bb9629115538, content=学习.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Mon Feb 26 19:53:09 CST 2018, time=2018-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289865, encodeId=87ae289865bd, content=****减少糖尿病患者胃癌风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Thu Feb 22 07:25:09 CST 2018, time=2018-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289580, encodeId=b56c28958013, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Wed Feb 21 06:12:30 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288968, encodeId=dc1b288968ff, content=谢谢.祝梅斯医学越来越好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Feb 18 18:31:38 CST 2018, time=2018-02-18, status=1, ipAttribution=)]
    2018-02-18 虈亣靌

    谢谢.祝梅斯医学越来越好!

    0

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