Nature:外伤性脑损伤的治疗方法

2014-01-14 Nature中文网 Nature中文网

外伤性脑损伤(经常是由交通事故造成的)是一个主要杀手和神经疾病的一个病因。 这项研究描述了一个闭锁性颅骨骨折小鼠模型,其病理与人类轻度外伤性脑损伤相似。 本文作者利用长期活体显微镜方法来研究从受伤开始起的损伤反应动态。他们利用该模型发现,实质细胞和脑膜细胞死亡可以通过“嘌呤能受体”对抗剂和抗氧化剂“谷胱甘肽”进行局部治疗来减少。 原文出处 Roth TL, Nayak D, Atanasi

外伤性脑损伤(经常是由交通事故造成的)是一个主要杀手和神经疾病的一个病因。【原文下载

这项研究描述了一个闭锁性颅骨骨折小鼠模型,其病理与人类轻度外伤性脑损伤相似。

本文作者利用长期活体显微镜方法来研究从受伤开始起的损伤反应动态。他们利用该模型发现,实质细胞和脑膜细胞死亡可以通过“嘌呤能受体”对抗剂和抗氧化剂“谷胱甘肽”进行局部治疗来减少。

原文出处

Roth TL, Nayak D, Atanasijevic T, Koretsky AP, Latour LL, McGavern DB.Transcranial amelioration of inflammation and cell death after brain injury.Nature. 2014 Jan 9【原文下载

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