J Oral Maxillofac Surg:单侧唇腭裂患者 上颌骨扩张刺激移植骨的生长

2018-08-07 杨帆 中国医学论坛报今日口腔

土耳其的一项研究显示,对于单侧唇腭裂患者,可考虑二期牙槽骨移植后扩张上颌骨来刺激移植骨的生长。该论文7月22日在线发表于《口腔颌面外科杂志》(J Oral Maxillofac Surg)。


土耳其的一项研究显示,对于单侧唇腭裂患者,可考虑二期牙槽骨移植后扩张上颌骨来刺激移植骨的生长。该论文7月22日在线发表于《口腔颌面外科杂志》(J Oral Maxillofac Surg)。

本研究为前瞻性对照临床试验。选取了30例完全恒牙列的单侧唇腭裂患者随机分为两组。Ⅰ组(平均年龄19.33±5.16岁)在二期牙槽骨移植前进行上颌骨缓慢扩张,Ⅱ组(平均年龄19.93±3.99岁)在二期牙槽骨移植后6周行上颌骨缓慢扩张,这两组的自体骨均取自髂骨。术后1周(T1)、6个月(T2)和12个月(T3)行CT检查。

术后6个月,Ⅰ组植骨体积的吸收量明显高于Ⅱ组(P=0.003),Ⅱ组的植骨密度明显高于Ⅰ组(P=0.017)。Ⅱ组虽然植骨吸收量少、密度较高,但在术后12个月后两组间的植骨平均体积和密度没有明显差异(P>0.05),Ⅰ组和Ⅱ组的植骨平均体积损失量分别为46.3%和34.6%,骨密度平均增加16%和49%。(杨帆 编译)

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    2018-09-17 lsj637
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    2019-06-10 医者仁心
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