Exp Ther Med:角膜切开联合巩膜切口手术治疗散光角膜移植术后高度散光的疗效评估

2019-02-11 MedSci MedSci原创

安徽医科大学第一附属医院眼科的Gu ZY和Ye MJ等人近日在Exp Ther Med杂志上发表了一篇文章,他们评估了散光角膜移植术(PKP)后,角膜切开术(AK)联合巩膜切口治疗高度散光的疗效、可预测性和安全性。

安徽医科大学第一附属医院眼科的Gu ZY和Ye MJ等人近日在Exp Ther Med杂志上发表了一篇文章,他们评估了散光角膜移植术(PKP)后,角膜切开术(AK)联合巩膜切口治疗高度散光的疗效、可预测性和安全性。

在进行PKP手术后,有8名患有高角膜散光[> 5.0屈光度(D)]患者的8只眼睛中,医生对散光中线上进行角膜切开术和巩膜切口手术联合治疗。研究者评估了术前和术后参数,包括未矫正视力(UCVA)、最佳矫正视力(BCVA)、屈光度和角膜屈光度。使用矢量分析的Alpins方法进行角膜散光变化程度评估。

结果表明,平均角膜散光在手术前后3个月具有显着的差异性,从术前的8.16±3.02D降至2.28±1.07D,在统计学上显着降低。平均UCVA从术前最小分辨角度(logMAR)的0.95±0.24提高到0.61±0.17 logMAR(P <0.05)。术前3个月平均BCVA从术前的0.41±0.18 logMAR提高到0.26±0.12 logMAR(P> 0.05)。手术后3至6个月,角膜散光保持稳定。Alpins方法分析证明,这种联合手术治疗方法效果良好,可预测性良好。手术引起的散光与目标诱导散光具有显着的相关性(r = 0.76,P <0.05)。没有患者出现任何严重的并发症。

本研究表明,角膜切开术(AK)结合巩膜切口手术对PKP后高度散光治疗有效,是一种相对可预测和安全的治疗方法。

原文出处:

Gu, Z.Y., et al., Effects of astigmatic keratotomy combined with scleral tunnel incisions for the treatment of high astigmatism after penetrating keratoplasty. Exp Ther Med, 2019. 17(1): p. 495-501.

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    2019-02-13 snowpeakxu
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    2019-02-11 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0