Sci Rep:月经初潮时出生体重与功能性卵巢储备之间相关性研究

2019-06-07 AlexYang MedSci原创

最近,有研究人员调查了月经初潮时,足月女性出生体重(BW)与功能性卵巢储备(FOR)之间的相关性,调查的女性年龄在34-35岁之间,并基于抗苗勒氏管激素(AMH)血清水平进行调查。研究的群体为1978年6月1日到1979年5月31日出生。主要研究结果为FOR的一个标记-血清AMH,以及与女性BW之间的关系,这些女性被分为小胎龄(SGA)、适中胎龄(AGA)和较大胎龄(LGA)。研究包括了274名女

最近,有研究人员调查了月经初潮时,足月女性出生体重(BW)与功能性卵巢储备(FOR)之间的相关性,调查的女性年龄在34-35岁之间,并基于抗苗勒氏管激素(AMH)血清水平进行调查。

研究的群体为1978年6月1日到1979年5月31日出生。主要研究结果为FOR的一个标记-血清AMH,以及与女性BW之间的关系,这些女性被分为小胎龄(SGA)、适中胎龄(AGA)和较大胎龄(LGA)。研究包括了274名女性,其中19名为SGA、238名为AGA和17名为LGA。平均的AMH浓度在SGA组(2.14ng/mL)、AGA组(2.13ng/mL)和LGA组(2.57ng/mL)之间没有显著的差异(p=0.11)。变量分析表明了3个组之间具有充分AMH水平的女性的比例也没有显出的差异(1ng/mL; p=0.11)。另外,在3个组之间,足月的34岁和35岁女性之间血清AMH浓度也没有显著的差异。

最后,研究人员指出,他们的样本大小足以检测存在的主要差异,并且基于AMH的血清浓度评估了月经初潮时足月女性出生体重与功能性卵巢储备之间的相关性。

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    2019-06-09 luwei00
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由此可见,这些研究结果表明出生体重与T2DM和CVD风险呈J型相关,并且这在女性中更为明显。