EASL 2014:难辨梭菌感染增加酒精性肝炎死亡率

2014-04-14 佚名 dxy

合并感染的酒精性肝炎(AH)患者死亡率较无感染者增加,但目前尚无资料表明日益增多的难辨梭状芽孢杆菌感染(CDI)对AH患者的影响。 美国洛杉矶加利福尼亚大学席达西尼医学中心的Sundaram等进行了一项研究,旨在探讨AH与CDI的相关性,以及合并梭状芽孢杆菌感染AH患者的住院周期及费用问题。 研究从全国住院样本数据库中检索出AH患者,应用多因素回归分析住院患者发生CDI的高危因素及AH患者死亡的危

合并感染的酒精性肝炎(AH)患者死亡率较无感染者增加,但目前尚无资料表明日益增多的难辨梭状芽孢杆菌感染(CDI)对AH患者的影响。

美国洛杉矶加利福尼亚大学席达西尼医学中心的Sundaram等进行了一项研究,旨在探讨AH与CDI的相关性,以及合并梭状芽孢杆菌感染AH患者的住院周期及费用问题。

研究从全国住院样本数据库中检索出AH患者,应用多因素回归分析住院患者发生CDI的高危因素及AH患者死亡的危险因素,评估CDI对AH患者住院周期的影响,应用泊松回归确定其对AH患者住院费用的影响。

研究结果显示,1.62%AH患者出现了CDI,且AH是CDI的危险因素(OR = 1.61),出现CDI的AH患者住院期间死亡率增加(OR = 1.75)、住院周期延长(10.63d vs 5.75d)、住院花费增多($36924.30 vs $29136.58)。

研究表明,AH是CDI的危险因素,且CDI可使AH患者的死亡率及医疗花费增加。因此AH患者需警惕CDI。

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    2014-04-16 kord1983
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    2014-04-16 lq1771
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