JAHA:左心室辅助装置患者残存三尖瓣返流的患病率、预测因子和预后价值

2018-07-04 xiangting MedSci原创

在LVAD支持超过1年的≈25%患者中观察到显著残存TR,并且与预后不良相关。

虽然植入左心室辅助装置(LVAD)通常在短期随访中可以改善三尖瓣返流(TR),但是在中长期LVAD支持的患者中残存TR的临床意义尚不清楚。这项研究旨在确定LVAD患者中,与三尖瓣(TV)变形相关残存TR的患病率、预测因子和预后价值。

研究队列包括127名接受LVAD植入而无TV手术的患者,其中使用LVAD支持至少1年。所有患者在术前和LVAD植入1年后接受超声心动图检查。通过TR彩色射流面积/右心房面积定量评估TR,显著性残存TR定义为随访超声心动图检查中≥20%的%TR。还进行了详细的超声心动图测量,其中包括TV环直径、TV小叶移位、左心室和右心室收缩功能。LVAD植入显著改善TR彩色射流面积/右心房面积比例以及左右心室收缩功能和束缚距离(P均<0.05),然而扩大了TV环直径(P=0.002)。30名患者中(23.6%)观察到显著的残存TR。年龄、术前TV环直径和残存二尖瓣返流与显著的残留TR相关(P均 <0.05),而TV束缚不相关。在平均随访21±17个月期间,残存TR患者的死亡率显著高于无残存TR的患者(log-rank P<0.001)。

在LVAD支持超过1年的≈25%患者中观察到显著残存TR,并且与预后不良相关。

原始出处:

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  5. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413232, encodeId=a61c141323232, content=<a href='/topic/show?id=1d7e48033f5' target=_blank style='color:#2F92EE;'>#左心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48033, encryptionId=1d7e48033f5, topicName=左心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15012955474, createdName=wushaoling, createdTime=Fri Jul 06 07:16:00 CST 2018, time=2018-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578460, encodeId=643015e8460e1, content=<a href='/topic/show?id=a1021962883' target=_blank style='color:#2F92EE;'>#三尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19628, encryptionId=a1021962883, topicName=三尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7cb16409801, createdName=124985dbm11(暂无昵称), createdTime=Fri Jul 06 07:16:00 CST 2018, time=2018-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329272, encodeId=50d03292e2c7, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/fhZdOu27e88Voqh19n8eF8cLplo8L4nicKtH0WnE3KFELXns5XDu8rsiceK2HHDZc2SEStia5VV3Pia2QLMVqlWbHw/0, createdBy=6e012139475, createdName=神功盖世, createdTime=Wed Jul 04 17:34:31 CST 2018, time=2018-07-04, status=1, ipAttribution=)]
    2018-07-06 zhaohui6731
  6. 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  7. 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    2018-07-04 神功盖世

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