Critical Care Medicine:患者危险饮酒模式与急性肾损伤有关

2019-08-16 不详 MedSci原创

不健康饮酒与急性肾损伤是否有关目前还有争论,过量饮酒是否会对重症患者肾功能的影响更是知之甚少。本项研究的目的是确定危险性饮酒是否与ICU和ICU出院时的急性肾损伤独立相关。

背景及目的:
不健康饮酒与急性肾损伤是否有关目前还有争论,过量饮酒是否会对重症患者肾功能的影响更是知之甚少。本项研究的目的是确定危险性饮酒是否与ICU和ICU出院时的急性肾损伤独立相关。

方法:
本项研究是一项前瞻性观察性队列研究。纳入了ICU中1107名成人患者,所有患者ICU停留时间大于或等于3天且可评估饮酒量。主要观察结局:急性肾损伤发生率。

结果:
本项研究共有320名高危饮酒者(29%)和787名非风险饮酒者(71%)入住ICU。这两组不同危险程度的饮酒患者的ICU入院时2-3期急性肾损伤患者的比例(42.5% vs 18%; p <0.0001),在风险高的饮酒者中显着高于非风险饮酒者,高风险饮酒与急性肾损伤显着相关(优势比,2.15; 1.60-2.89; p <0.0001),本项研究共有22%的高风险饮酒者和9%的无风险饮酒者出院时患有急性肾损伤 2-3期(p <0.001)。

结论:
本项研究结果表明,重症患者的慢性饮酒不及酒精滥用与肾功能不全有关。

原始出处:

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    2019-08-28 kalseyzl
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    2019-10-13 jeanqiuqiu
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