Heart:年龄、时期和队列效应对心脑血管疾病死亡率的影响

2020-03-30 MedSci原创 MedSci原创

本研究目的旨在探讨年龄、时期或队列效应是否能解释苏格兰缺血性心脏病(IHD)和脑血管病(CeVD)死亡率的趋势和不平等。

本研究目的旨在探讨年龄、时期或队列效应是否能解释苏格兰缺血性心脏病(IHD)和脑血管病(CeVD)死亡率的趋势和不平等。

从20世纪80年代末开始,CeVD死亡率稳步提高,而IHD死亡率迅速提高。年龄效应很明显,这两个结果都显示出与年龄呈指数关系,除了1980年代和1990年代的IHD男性。对于IHD患者,随着年龄的增长,男性比女性的风险增加有所减少,41-50岁男性的发病率为4.28(95%可信区间4.12-4.44),71-80岁为1.17(95%可信区间1.16-1.18)。随着时间的推移,按地区划分的IHD死亡率的不平等现象持续存在。20世纪80年代末以后,CeVD死亡率的不平等现象有所增加。

研究结果显示,苏格兰的缺血性心脏病和脑血管病死亡率表现出明显的年龄效应,但近期的时期和队列效应不明显。

原始出处:

Jane P et al.Do age, period or cohort effects explain circulatory disease mortality trends, Scotland 1974–2015? Heart.2020 Mar.

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    2020-04-01 zhaojie88
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    2020-04-01 slcumt

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