GUT:英国消化内科学会关于结肠和直肠锯齿状息肉的重要声明

2017-05-02 MedSci MedSci原创

在过去的十年中,已经认识到锯齿状息肉是一种重要的癌前病变,其占结直肠癌的15%至30%。因此,临床迫切需要相关指导,以便管理这些病变。然而,目前关于此疾病的证据基础十分有限。近期,英国消化内科学会(BSG)内窥镜检查部门审查了现有的证据,并在杂志GUT上发表了重要的立场声明,提供临床相关指导;直到有相关证据可用于支持正式的指南为止。此项立场声明的范围广泛,包括:锯齿状病变具有恶变潜力的相关证据;锯

在过去的十年中,已经认识到锯齿状息肉是一种重要的癌前病变,其占结直肠癌的15%至30%。因此,临床迫切需要相关指导,以便管理这些病变。然而,目前关于此疾病的证据基础十分有限。


近期,英国消化内科学会(BSG)内窥镜检查部门审查了现有的证据,并在杂志GUT上发表了重要的立场声明,提供临床相关指导;直到有相关证据可用于支持正式的指南为止。

此项立场声明的范围广泛,包括:锯齿状病变具有恶变潜力的相关证据;锯齿状病变的检测和切除;检测到锯齿状病变后的监测策略;一些特殊情况-锯齿状息肉病综合征(包括手术)和结肠炎中的锯齿状病变;教育、审计和基准和研究问题。

目前,提出了有关这些问题的声明,认为证据是足够的,并通过德尔菲进程重新评估,直至达成> 80%的协议。

使用建议书、评估、开发和评估(GRADE)工具评估证据的强度和最终声明建议的强度。

主要建议为:直到发现有关监测的有效性或其他方面的进一步证据,患有无梗塞的锯齿状病变(SSL)的患者与未来发生肿瘤或结肠直肠癌的高风险相关(SSL≥10mm或具有不典型增生的锯齿状病变,包括传统的锯齿状腺瘤),应在3年内进行一次性结肠镜检查(弱推荐,低质量证据,90%一致)。

原始出处:
East JE, Atkin WS , et al. British Society of Gastroenterology position statement on serrated polyps in the colon and rectum. Gut. 2017 Apr 27. pii: gutjnl-2017-314005. doi: 10.1136/gutjnl-2017-314005. 

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    2017-05-10 jyzxjiangqin

    结肠和直肠锯齿状息肉的相关问题。

    0

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content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Tue May 02 14:20:11 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-08 ylzr123

    感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了,点个赞吧!

    0

  4. 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content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Tue May 02 14:20:11 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-06 sfb591110

    谢谢

    0

  5. 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content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Tue May 02 14:20:11 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-03 wxl882001

    学习一下

    0

  7. 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CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195168, encodeId=6f3519516842, content=感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了,点个赞吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon May 08 05:48:15 CST 2017, time=2017-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194585, encodeId=567219458561, content=谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQARsVTQlGkb8xg4wNC2SBgoxvlIMpiaibIgUJh5ibtmCCj2hv9e7bzLL0KaNRFXcsLReiaFYDtDdbqWB1/0, createdBy=5fbb1577691, createdName=sfb591110, createdTime=Sat May 06 13:34:20 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1544866, encodeId=cf2615448664f, content=<a href='/topic/show?id=750d65e32e3' target=_blank style='color:#2F92EE;'>#消化内科#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65732, encryptionId=750d65e32e3, topicName=消化内科)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=be8e13667406, createdName=1249897bm41(暂无昵称), createdTime=Thu May 04 03:24:00 CST 2017, time=2017-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193340, encodeId=0f6b1933401f, content=学习一下, beContent=null, objectType=article, channel=null, level=null, 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content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Tue May 02 14:20:11 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-03 tanxingdoctor

    学习了谢谢分享

    0

  8. 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content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Tue May 02 14:20:11 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-03 往日如昨

    学习了谢谢分享

    0

  9. 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content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Tue May 02 14:20:11 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-03 ylzr123

    感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了,点个赞吧!

    0

  10. 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encodeId=fa86193181f6, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Wed May 03 08:26:31 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193070, encodeId=8adc1930e089, content=感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了,点个赞吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed May 03 05:44:56 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=192925, encodeId=55d719292508, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Tue May 02 14:20:11 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-02 1ddf3e1dm99(暂无匿称)

    学习了,谢谢

    0

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