J Sex Med:免疫缺陷不会增加充气式阴茎假体的再手术率

2021-08-09 AlexYang MedSci原创

据推测,免疫力低下的患者的术后感染率较高。

据推测,免疫力低下的患者的术后感染率较高。

近期,有研究人员在免疫力低下的男性中,调查了是否充气式阴茎假体(IPP)的再手术率(由于感染、侵蚀、设备故障或患者不满意)更高

研究人员分析了2000年至2016年在纽约州规划和研究合作系统数据库中初次接受IPP植入的男性。免疫力低下的患者与免疫力正常的患者以1:3的比例进行倾向性评分匹配。通过进行Kaplan Meier分析和Log-rank测试,研究人员估计并比较了免疫力低下的男性和对照组在随访30天、90天、1年和3年时的再手术率(包括切除、因感染而再手术、修正或更换IPP),建立了Cox比例风险模型来研究免疫缺陷状态与再次手术风险之间的整体关联。

研究人员共确定了245名在2000年至2016年间接受初次IPP的免疫缺陷患者。经过倾向性评分匹配,他们分析了235名免疫力低下的男性和705名对照组。在任何评估的时间段内(30天、90天、1年或3年),免疫力低下的男性和对照组之间的总体再手术率没有差异。在Cox比例风险模型中,总体再手术、切除或修正/替换的风险(分别为HR 1.11 [95% CI 0.74-1.67], HR 1.58 [95% CI 0.90-2.79] 和HR 0.83 [95% CI 0.47-1.45])在免疫受损男性和对照组之间没有明显差异。感染引起的再手术在免疫力低下的男性和免疫力正常的男性之间也没有显著差异(HR 2.06 [95% CI 0.97-4.40])。

免疫底下男性和对照的总体再手术率,移除率,修正率或者置换率比较

综上所述,再手术率,包括因感染引起的再手术率,在免疫力低下的男性和免疫力正常的对照组之间没有明显差异。因此,在适当选择的候选者中,免疫状态似乎并没有使患者面临更高的移植或修正风险

原始出处:

Christopher D Gaffney , Jonathan Fainberg , Nahid Punjani et al. Immune Deficiency Does Not Increase Inflatable Penile Prosthesis Reoperation Rates. J Sex Med. Aug 2021

 

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    2021-10-14 ewsr11
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    2021-08-09 1e1606abm78(暂无匿称)

    很有临床指导意义

    0

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