Ann Allergy Asthma Immunol:鼻炎发病率及与给特应性皮炎的关系

2021-03-20 AlexYang MedSci原创

特应性皮炎(AD)和鼻炎是常见的特应性疾病,由于病理生理学上的重叠有可能同时发生。

特应性皮炎(AD)和鼻炎是常见的特应性疾病,由于病理生理学上的重叠有可能同时发生

虽然这两种疾病的大多数情况下是轻微的,可用局部抗炎药物治疗,而这两种疾病的2型炎症靶向系统和生物治疗的出现,为进一步深入了解AD和鼻炎的确切重叠提供了依据。最近,有研究人员确定了AD和鼻炎之间的关联。他们对AD和鼻炎之间的关系进行系统回顾和元分析。根据系统性评估和元分析的首选报告项目(PRISMA)指南,对数据库Pubmed、Embase和CNKI进行了系统性回顾和元分析。

检索结果产生了10422次引用,分别有341篇和302篇纳入定性和定量分析中。特应性皮炎患者鼻炎的合并患病率为40.5%(95%CI 39.0-42.0),无特应性皮炎个体为18.0%(95%CI 16.7-19.2)。AD患者同时患有鼻炎和哮喘的合并患病率为14.2%(95%CI 13.0-15.5)。AD分别与鼻炎(OR 3.00,95%CI 2.83-3.18)、过敏性鼻炎(OR 3.25,95%CI 2.26-4.66)和非过敏性鼻炎(OR 1.99,95%CI 1.39-2.86)存在相关性。

最后,研究人员指出,鼻炎(包括过敏性和非过敏性形式)在AD患者中非常常见未来的调查应明确针对这两种疾病的药物应如何适用于这些患者

原始出处:

Mette Hjorslev Knudgaard , Thomas Holger Andreasen , Nanna Ravnborg et al. Rhinitis prevalence and association with atopic dermatitis: A systematic review and meta-analysis. Ann Allergy Asthma Immunol. Mar 2021

 

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    2021-07-25 skhzy
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    2021-03-22 膀胱癌

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