adiology:2D US横波弹性成像在慢性乙肝患者肝硬化的价值

2019-02-24 shaosai MedSci原创

本研究旨在验证2D 横波弹性成像(SWE)在慢性乙肝的诊断价值。

本研究旨在验证2D 横波弹性成像(SWE)在慢性乙肝的诊断价值。

本研究在12个医院进行,共纳入了654例慢性乙肝并行肝脏活检及2D SWE检查的患者。受试者被分为慢性感染和慢性肝炎组。利用德龙检验与天冬氨酸氨基转移酶-血小板比值指数(APRI)、肝硬化-4指数(FIB-4)、瞬时弹性成像(TE)比较,验证2D SWE的诊断价值,并在两亚组进行比较。利用多水平比值比分析确定肝硬化双最佳截断值。

结果为,总共有402例慢性乙肝受试者纳入研究(154例慢性感染和248例慢性肝炎)。2D SWE曲线下面积(0.87; 95%CI: 0.83, 0.90)要显着高于TE(0.80; 95% CI: 0.68, 0.88)、APRI(0.70; 95% CI: 0.65, 0.74)和FIB-4(0.73; 95% CI: 0.69, 0.78)。慢性感染的曲线下面积最高(0.92; 95% CI: 0.87, 0.96),且显着高于慢性乙肝组(0.84; 95% CI: 0.78, 0.88; P = .017)。双最佳截断值且似然比为<0.1和大于10能够有效检出慢性感染。共有81.2% (125/154)例肝硬化患者被诊断。

本研究表明,2D横波弹性成像(SWE)要在诊断肝硬化要优于其他无创性检查方法。2D SWE在诊断和排除慢性肝脏感染患者肝硬化具有诊断价值,有助于抗病毒治疗。

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    2019-03-13 jyzxjiangqin

    慢性乙肝患者的治疗。

    0

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    2019-02-24 guging

    谢谢!最新的信息读起来就是收获大

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1671774, encodeId=ab3d16e17745f, content=<a href='/topic/show?id=0bcc2342943' target=_blank style='color:#2F92EE;'>#乙肝患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23429, encryptionId=0bcc2342943, topicName=乙肝患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1826842253, createdName=sjzlzc016, createdTime=Sat Jun 01 23:19:00 CST 2019, time=2019-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2053555, encodeId=6b90205355535, content=<a href='/topic/show?id=eea6630010b' target=_blank style='color:#2F92EE;'>#横波弹性成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63001, encryptionId=eea6630010b, topicName=横波弹性成像)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Sun Oct 06 14:19:00 CST 2019, time=2019-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1645977, encodeId=b72a16459e7ff, content=<a href='/topic/show?id=663550088ef' target=_blank style='color:#2F92EE;'>#弹性成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50088, encryptionId=663550088ef, topicName=弹性成像)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0eb23278887, createdName=tamgche, createdTime=Sat Sep 07 04:19:00 CST 2019, time=2019-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=362584, encodeId=47ac36258452, content=慢性乙肝患者的治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Mar 13 19:35:28 CST 2019, time=2019-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046378, encodeId=0b7510463e865, content=谢谢!最新的信息读起来就是收获大, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Sun Feb 24 13:19:00 CST 2019, time=2019-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=361407, encodeId=699936140ee2, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Sun Feb 24 12:01:51 CST 2019, time=2019-02-24, status=1, ipAttribution=)]
    2019-02-24 183****7028

    学习

    0