Eur Respir J:艾滋病病毒感染者非传染性肺疾病负担增加

2018-09-23 xing.T MedSci原创

由此可见,在PLHIV中发生非感染性肺疾病,特别是COPD、肺气肿、肺纤维化、PAH和慢性呼吸道疾病,这表明对该人群中进行大规模筛查是正确的。

艾滋病病毒感染者(PLHIV)艾滋病发病率的总体降低以及肺疾病谱发生了变化。近日,呼吸疾病领域权威杂志Eur Respir J上发表了一篇研究文章,研究人员旨在更新法国住院的PLHIV肺疾病患病率的流行病学的最新情况。

研究人员分析了从法国全国医院医疗信息数据库中获取的2007年至2013年期间法国住院的PLHIV的肺疾病患病率,并评估了4年随访期间艾滋病与非传染性疾病之间的关系。

2007年至2013年期间,共有52091名PLHIV在法国住院治疗。在住院治疗肺疾病的PLHIV中,非传染性肺病在2007年至2013年期间从45.6%显著增加至54.7%,但是至少有一次感染性肺疾病的患者比例显著下降。2010年,研究人员将10067名普遍住院的PLHIV与8244 682名非PLHIV住院患者进行了比较。在30-49岁的患者中,即使在调整吸烟后,HIV感染也与慢性阻塞性肺病(COPD)、慢性呼吸衰竭、肺气肿、肺纤维化和肺动脉高压(PAH)有关。

由此可见,在PLHIV中发生非感染性肺疾病,特别是COPD、肺气肿、肺纤维化、PAH和慢性呼吸道疾病,这表明对该人群中进行大规模筛查是正确的。

原始出处:

Thomas Maitre,et al. Increasing burden of noninfectious lung disease in persons living with HIV: a 7-year study using the French nationwide hospital administrative database. Eur Respir J. 2018. http://erj.ersjournals.com/content/52/3/1800359

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    2019-07-30 xzw113
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    2018-09-23 lietome15

    好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!

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