Biological Psychiatry子刊:年轻大麻吸食者的社会排斥反应并不相同

2016-03-30 MedSci MedSci原创

既往研究报告,同龄是预测青少年和年轻成人使用大麻的最重要的其中一个因素,但是尚未有研究探究吸食大麻者的社会处理的神经关联。

既往研究报告,同龄是预测青少年和年轻成人使用大麻的最重要的其中一个因素,但是尚未有研究探究吸食大麻者的社会处理的神经关联。

本研究共纳入了20名吸食大麻的年轻人和22名不吸食大麻的对照人群,所有研究对象参与一个称为Cyberball的神经影像学社会排斥的任务,这是一种电脑抛球游戏,抛出预定数目的球后参与者被退出比赛。

对照组人群在被退出游戏之后,其脑岛被明显激活,这是与消极情绪有关的大脑区域。在同伴被退出游戏后,两组人群的大脑腹侧前扣带皮层都被激活,这是与情感监测有关的一个大脑区域。只有大麻组人群的腹侧前扣带皮层激活和自我报告的同伴合作评分之间具有关联。

总而言之,该研究表明,吸食大麻者在面对社会排斥时表现出非典型性的神经处理。这种激活的差异可能先于吸食大麻存在并可能导致吸食大麻者发病,以及/或吸食大麻导致了这种结果。

原始出处:

Jodi M. Gilman, Max T. Curran, et al., Altered Neural Processing to Social Exclusion in Young Adult Marijuana Users. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, March 2016, Pages 152–159.

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    2016-10-15 sunylz
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    2016-04-01 kcb069
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